HitPredict

Interactor 1: SWD1 (P39706)
COMPASS component SWD1 (Complex proteins associated with SET1 protein SWD1) (Set1C component SWD1)
Gene: SWD1

Interactor 2: PFS2 (P42841)
Polyadenylation factor subunit 2
Gene: PFS2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	12453421
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 426 Sc			1 465
+	Hs
		254111 WDR1_HUMAN (10-250): 8.34e-37: 143: 24.10		FBXW7_HUMAN (162-460): 3.24e-68: 232: 18.63
+	Sp
		999842 TUP11_SCHPO (152-425): 2.83e-43: 161: 12.72		TUP12_SCHPO (31-250): 5.46e-54: 191: 16.74
+	Hs
		903242 RBBP5_HUMAN (1-397): 2.09e-78: 254: 28.15		WDR5_HUMAN (344-460): 7.26e-19: 89.1: 12.30
+	Mm
		903670 RBBP5_MOUSE (1-397): 4.12e-78: 253: 28.15		WDR5_MOUSE (344-460): 7.26e-19: 89.1: 12.30
+	Dr
		1193337 Q7ZUU9_DANRE (1-397): 7.04e-78: 252: 28.15		Q7ZTX2_DANRE (344-460): 2.03e-18: 88: 12.30
+	Hs
		1070736 RBBP5_HUMAN (1-397): 2.09e-78: 254: 28.15		WDR5B_HUMAN (333-460): 3.08e-17: 84.5: 14.29
+	Hs
		1346954 NLE1_HUMAN (243-415): 3.68e-22: 100: 10.92		NLE1_HUMAN (168-460): 1.4e-68: 228: 14.78
+	Hs
		1240442 POC1A_HUMAN (157-426): 6.52e-44: 159: 9.63		POC1B_HUMAN (248-461): 9.49e-45: 164: 13.70
+	Sp
		999838 TUP11_SCHPO (152-425): 2.83e-43: 161: 12.72		TUP11_SCHPO (244-460): 3.08e-41: 157: 15.42
+	Hs
		1288273 WDR83_HUMAN (7-346): 7.02e-66: 214: 13.78		SNR40_HUMAN (335-461): 1.7e-18: 88.3: 11.28
+	Hs
		197071 SNR40_HUMAN (7-136): 3.56e-30: 121: 16.42		PRP4_HUMAN (205-464): 1.43e-47: 173: 14.29
+	Hs
		196984 WDR5_HUMAN (245-419): 2.37e-22: 98.8: 11.74		PRP4_HUMAN (205-464): 1.43e-47: 173: 14.29
+	Sc
		630844 NLE1_YEAST (243-422): 2.36e-23: 104: 10.50		NLE1_YEAST (302-464): 2.54e-32: 130: 10.35
+	Hs
		921751 NLE1_HUMAN (243-415): 3.68e-22: 100: 10.92		GBB2_HUMAN (193-448): 1.18e-32: 128: 17.69
+	Hs
		792949 LIS1_HUMAN (210-422): 6.1e-33: 130: 9.86		WDR5_HUMAN (344-460): 7.26e-19: 89.1: 12.30
+	Mm
		925836 LIS1_MOUSE (210-422): 4.7e-33: 130: 9.86		LIS1_MOUSE (344-460): 2.08e-16: 82.9: 13.12
+	Hs
		792935 LIS1_HUMAN (210-422): 6.1e-33: 130: 9.86		LIS1_HUMAN (344-460): 2.38e-16: 82.6: 13.12
+	Hs
		903428 SNR40_HUMAN (7-136): 3.56e-30: 121: 16.42		WDR5_HUMAN (344-460): 7.26e-19: 89.1: 12.30
+	Hs
		903551 NLE1_HUMAN (243-415): 3.68e-22: 100: 10.92		WDR5_HUMAN (344-460): 7.26e-19: 89.1: 12.30