Protein: CENPO
Inner kinetochore subunit MCM21 (CENP-O homolog) (Chromosome transmission fidelity protein 5) (Constitutive centromere-associated network protein MCM21) (Minichromosome maintenance protein 21)

Gene: CENPO, MCM21
Organism: Saccharomyces cerevisiae S288C
Interactions: 77
UniProt ID: Q06675

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0000817 - COMA complex
GO:0008608 - attachment of spindle microtubules to kinetochore
GO:0034087 - establishment of mitotic sister chromatid cohesion
GO:0034508 - centromere complex assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

757229

CENPN
Inner kinetochore subunit CHL4

3

0

Small-scale

0.784

High

748305

CENPU
Inner kinetochore subunit AME1

9

1

Small-scale

0.750

High

861319

CENPQ
Inner kinetochore subunit OKP1

5

1

Small-scale

0.721

High

988562

CENPO
Inner kinetochore subunit MCM21

2

0

Small-scale

0.718

High

972074

CENPP
Inner kinetochore subunit CTF19

6

0

Small-scale

0.702

High

775874

DSN1
Kinetochore-associated protein DSN1

6

0

Small-scale

0.688

High

988574

CENPH
Inner kinetochore subunit MCM16

5

0

Small-scale

0.684

High

747533

CENPL
Inner kinetochore subunit IML3

4

0

High-throughput

0.648

High

812580

CENPK
Inner kinetochore subunit MCM22

3

0

High-throughput

0.622

High

988581

CENPI
Inner kinetochore subunit CTF3

3

0

Small-scale

0.622

High

747753

SLI15
Inner centromere protein-related protein SLI15

2

0

Small-scale

0.581

High

716105

CENPC
Inner kinetochore subunit MIF2

2

0

Small-scale

0.575

High

763957

MTW1
Kinetochore-associated protein MTW1

2

0

Small-scale

0.569

High

812438

NNF1
Kinetochore-associated protein NNF1

2

0

Small-scale

0.569

High

798065

CENPT
Inner kinetochore subunit CNN1

2

0

Small-scale

0.547

High

986219

NKP2
Inner kinetochore subunit NKP2

1

0

High-throughput

0.493

High

565167

CBF1
Centromere-binding protein 1

1

0

Small-scale

0.486

High

853184

SKP1
Suppressor of kinetochore protein 1

1

0

Small-scale

0.486

High

979637

SPC24
Kinetochore protein SPC24

1

0

Small-scale

0.486

High

412593

CDC7
Cell division control protein 7

1

0

Small-scale

0.480

High

687555

DBF4
DDK kinase regulatory subunit DBF4

1

0

Small-scale

0.480

High

766829

SPC25
Kinetochore protein SPC25

1

0

Small-scale

0.460

High

988573

RIO1
Serine/threonine-protein kinase RIO1

1

0

Small-scale

0.460

High

708062

NUF2
Kinetochore protein NUF2

1

0

Small-scale

0.458

High

746232

SHE1
Mitotic spindle-associated protein SHE1

1

0

Small-scale

0.458

High

774080

NDC80
Kinetochore protein NDC80

1

0

Small-scale

0.458

High

859678

SP105
Spindle pole body component SPC105

1

0

Small-scale

0.458

High

859862

YBP2
YAP1-binding protein 2

1

0

Small-scale

0.458

High

977818

FIN1
Filament protein FIN1

1

0

Small-scale

0.458

High

979524

KRE28
Spindle pole body component KRE28

1

0

High-throughput

0.458

High

988579

NKP1
Inner kinetochore subunit NKP1

1

0

High-throughput

0.458

High

988569

RBX1
RING-box protein HRT1

1

0

High-throughput

0.438

High

988570

NSL1
Kinetochore-associated protein NSL1

1

0

High-throughput

0.426

High

730925

CENPA
Histone H3-like centromeric protein CSE4

4

0

Small-scale

0.350

High

972918

IMA1
Importin subunit alpha

1

0

High-throughput

0.282

High

977398

NSE5
Non-structural maintenance of chromosome element 5

1

0

High-throughput

0.282

High

704971

PRP18
Pre-mRNA-splicing factor 18

1

0

High-throughput

0.269

Low

775269

ULP2
Ubiquitin-like-specific protease 2

1

0

Small-scale

0.261

Low

663425

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

860816

RRP46
Exosome complex component RRP46

1

0

High-throughput

0.249

Low

988572

PSH1
RING finger protein PSH1

1

0

Small-scale

0.249

Low

345250

ATIF
F(1)-ATPase inhibitor IF(1), mitochondrial

1

0

High-throughput

0.238

Low

424018

COX9
Cytochrome c oxidase subunit 9, mitochondrial

1

0

High-throughput

0.238

Low

565294

SPO12
Sporulation-specific protein 12

1

0

High-throughput

0.238

Low

753315

YHE2
Putative uncharacterized protein YHL042W

1

0

High-throughput

0.238

Low

756156

CHS7
Chitin synthase export chaperone

1

0

High-throughput

0.238

Low

756640

PTH
Peptidyl-tRNA hydrolase

1

0

High-throughput

0.238

Low

765916

YEH8
Uncharacterized protein YEL068C

1

0

High-throughput

0.238

Low

766964

RSMB
Small nuclear ribonucleoprotein-associated protein B

1

0

High-throughput

0.238

Low

767045

EDC2
Enhancer of mRNA-decapping protein 2

1

0

High-throughput

0.238

Low

767459

YER4
Uncharacterized protein YER084W

1

0

High-throughput

0.238

Low

774100

YIO1
Putative uncharacterized protein YIL141W

1

0

High-throughput

0.238

Low

778920

RMRP
Ribonuclease MRP protein subunit SNM1

1

0

High-throughput

0.238

Low

780554

RS29B
Small ribosomal subunit protein uS14B

1

0

High-throughput

0.238

Low

797259

YFB5
Uncharacterized protein YFL015C

1

0

High-throughput

0.238

Low

798131

YFM4
Uncharacterized protein YFR054C

1

0

High-throughput

0.238

Low

816935

ECL1
Extender of the chronological lifespan protein 1

1

0

High-throughput

0.238

Low

858875

YGY9
Putative uncharacterized protein YGL239C

1

0

High-throughput

0.238

Low

860176

YG1C
Uncharacterized protein YGR018C

1

0

High-throughput

0.238

Low

860280

CAX4
Dolichyldiphosphatase

1

0

High-throughput

0.238

Low

953545

YD455
Putative uncharacterized protein YDR455C

1

0

High-throughput

0.238

Low

974374

PAU10
Seripauperin-10

1

0

High-throughput

0.238

Low

988563

YD050
Putative uncharacterized protein YDL050C

1

0

High-throughput

0.238

Low

988564

PBP4
Protein PBP4

1

0

High-throughput

0.238

Low

988565

OPI6
Putative uncharacterized protein OPI6

1

0

High-throughput

0.238

Low

988566

YD118
Putative uncharacterized protein YDL118W

1

0

High-throughput

0.238

Low

988567

IRC19
Increased recombination centers protein 19

1

0

High-throughput

0.238

Low

988568

YL037
Putative uncharacterized protein YLL037W

1

0

High-throughput

0.238

Low

988571

YDL26
Putative uncharacterized protein YDL026W

1

0

High-throughput

0.238

Low

988575

YD162
Putative uncharacterized protein YDL162C

1

0

High-throughput

0.238

Low

988576

YD041
Putative uncharacterized protein YDL041W

1

0

High-throughput

0.238

Low

988577

SNU23
23 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.238

Low

988578

NPC2
Phosphatidylglycerol/phosphatidylinositol transfer protein

1

0

High-throughput

0.238

Low

988580

TMA17
Translation machinery-associated protein 17

1

0

High-throughput

0.238

Low

495063

HSP72
Heat shock protein SSA2

1

0

High-throughput

0.232

Low

512873

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024