HitPredict

Interactor 1: RBG1 (P39729)
Ribosome-interacting GTPase 1 (GTP-binding protein RBG1) (Genetically interacts with ribosomal genes protein 1)
Gene: RBG1

Interactor 2: GIR2 (Q03768)
Protein GIR2 (DRG family-regulatory protein 2) (Genetically interacts with ribosomal genes protein 2)
Gene: GIR2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.695

Property	Details
Experiments	10688190, 18719252, 19448108, 37968396
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002181 - cytoplasmic translation GO:0005737 - cytoplasm GO:1903833 - positive regulation of cellular response to amino acid starvation
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 369 Sc			1 265
+	Sc
		861254 RBG2_YEAST (3-369): 3.55e-111: 330: 50.95		GIR2_YEAST (1-265): 3.59e-98: 290: 100.00
+	Hs
		1330587 DRG1_HUMAN (1-369): 1.1e-131: 382: 65.58		RWDD1_HUMAN (2-251): 7.39e-52: 171: 29.25
+	Hs
		874246 DRG2_HUMAN (3-369): 5.64e-131: 380: 54.50		RWDD1_HUMAN (2-251): 7.39e-52: 171: 29.25
+	Mm
		686245 DRG1_MOUSE (1-369): 6.32e-132: 383: 65.58		RWDD1_MOUSE (2-251): 1.07e-50: 167: 29.25
+	Mm
		1321751 DRG2_MOUSE (3-369): 3.09e-131: 381: 55.04		RWDD1_MOUSE (2-251): 1.07e-50: 167: 29.25