HitPredict

Interactor 1: SLN1 (P39928)
Osmosensing histidine protein kinase SLN1 (EC 2.7.13.3) (Osmolarity two-component system protein SLN1) (Tyrosine phosphatase-dependent protein 2)
Gene: SLN1

Interactor 2: SSK1 (Q07084)
Osmolarity two-component system protein SSK1
Gene: SSK1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	11073911
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HATPase_c~Response_reg, HisKA~Response_reg, Response_reg~Response_reg
Common GO terms	GO:0007234 - osmosensory signaling via phosphorelay pathway
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1220 Sc			1 712
+	Sc
		757067 SLN1_YEAST (1-1220): 0: 1276: 100.00		SKN7_YEAST (464-698): 7.58e-39: 154: 23.14
+	Sc
		764823 SLN1_YEAST (1-1220): 0: 1276: 100.00		SLN1_YEAST (424-651): 7.47e-34: 141: 22.63
+	At
		1319760 AHK4_ARATH (365-1208): 1.37e-123: 410: 21.25		AHK3_ARATH (289-712): 4.84e-30: 129: 10.80
+	At
		1319776 AHK2_ARATH (349-1211): 8.58e-111: 377: 17.56		AHK2_ARATH (288-704): 1.51e-32: 137: 11.83
+	At
		1319771 AHK2_ARATH (349-1211): 8.58e-111: 377: 17.56		AHK3_ARATH (289-712): 4.84e-30: 129: 10.80
+	Mx
		1091250 Q1CVV2_MYXXD (443-815): 1.61e-39: 160: 18.25		Q1D8M1_MYXXD (325-654): 7.61e-60: 220: 14.72
+	At
		186803 CKI1_ARATH (538-1214): 8.33e-77: 278: 17.56		CKI1_ARATH (505-635): 3.93e-15: 81.8: 23.97
+	At
		826141 EIN4_ARATH (1021-1211): 1e-33: 142: 24.23		ETR1_ARATH (321-654): 9.52e-57: 208: 13.06
+	At
		826111 ERS1_ARATH (644-951): 1.52e-32: 137: 14.47		ETR1_ARATH (321-654): 9.52e-57: 208: 13.06
+	Bt
		1206291 Q8A3A5_BACTN (894-1214): 2.98e-31: 135: 16.72		Q8A3A5_BACTN (336-712): 6.37e-55: 206: 13.95
+	Mx
		1091248 Q1CVV2_MYXXD (443-815): 1.61e-39: 160: 18.25		Q1D1K9_MYXXD (505-712): 6.56e-47: 167: 15.00
+	At
		1012931 EIN4_ARATH (1021-1211): 1e-33: 142: 24.23		ETR2_ARATH (432-649): 5.21e-34: 141: 17.98
+	Cv
		3005 A0A0H3CCG1_CAUVN (700-936): 2.48e-34: 144: 17.72		A0A0H3C9D0_CAUVN (504-652): 9.4e-34: 127: 24.16
+	Ss
		937527 Q55838_SYNY3 (619-1070): 3.52e-44: 175: 16.74		P72936_SYNY3 (504-644): 1.6e-15: 81: 22.70
+	Sp
		144036 MAK2_SCHPO (501-859): 1.95e-40: 165: 17.25		MAK3_SCHPO (505-646): 1e-15: 83.7: 23.45
+	Ss
		938478 P73519_SYNY3 (582-925): 5.6e-35: 147: 18.61		P73828_SYNY3 (326-647): 8.86e-17: 86.8: 10.23
+	Mx
		1091251 Q1CVV2_MYXXD (443-815): 1.61e-39: 160: 18.25		Q1D948_MYXXD (322-467): 5.91e-11: 68: 9.87