HitPredict

Interactor 1: LIS1 (P39946)
Nuclear distribution protein PAC1 (Lissencephaly-1 homolog) (LIS-1) (nudF homolog)
Gene: PAC1

Interactor 2: LIS1 (P39946)
Nuclear distribution protein PAC1 (Lissencephaly-1 homolog) (LIS-1) (nudF homolog)
Gene: PAC1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.919

The method score is based on:

Property Details
Experiments 18719252, 34994688, 15965467, 22875988, 22939623
Identification Methods two hybrid, x-ray crystallography, affinity chromatography technology, cross-linking study, molecular sieving
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains WD40~WD40
Common GO terms GO:0000132 - establishment of mitotic spindle orientation
GO:0000776 - kinetochore
GO:0000922 - spindle pole
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
and 13 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 494
Sc

1 494
+ Hs
+ Ce
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Sc
+ Sp
+ Hs
+ Sp
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024