HitPredict

Interactor 1: LIS1 (P39946)
Nuclear distribution protein PAC1 (Lissencephaly-1 homolog) (LIS-1) (nudF homolog)
Gene: PAC1

Interactor 2: UBC7 (Q02159)
Ubiquitin-conjugating enzyme E2 7 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 7) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-18 kDa) (Ubiquitin-protein ligase)
Gene: UBC7

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	14690591
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 494 Sc			1 165
+	Hs
		921784 GBB2_HUMAN (239-493): 1.78e-35: 136: 16.35		UB2D4_HUMAN (4-164): 1.63e-73: 218: 36.65
+	Hs
		849304 GBB2_HUMAN (239-493): 1.78e-35: 136: 16.35		UB2D1_HUMAN (4-164): 7.38e-73: 217: 36.65
+	Hs
		919704 GBB2_HUMAN (239-493): 1.78e-35: 136: 16.35		UB2D2_HUMAN (4-164): 1.2e-72: 216: 36.03
+	Hs
		895772 GBB2_HUMAN (239-493): 1.78e-35: 136: 16.35		UB2D3_HUMAN (4-164): 2.23e-71: 213: 36.03
+	Hs
		908255 GBB2_HUMAN (239-493): 1.78e-35: 136: 16.35		UB2G1_HUMAN (4-162): 7.38e-69: 207: 50.00
+	Dm
		218245 O44382_DROME (129-286): 4.57e-14: 76.5: 14.78		UBCD1_DROME (4-164): 3.2e-72: 215: 36.65
+	Hs
		891447 FBW1B_HUMAN (129-286): 3.08e-14: 76.9: 14.29		UB2G2_HUMAN (1-165): 1.05e-71: 214: 62.42
+	Hs
		895947 FBW1B_HUMAN (129-286): 3.08e-14: 76.9: 14.29		UB2D3_HUMAN (4-164): 2.23e-71: 213: 36.03
+	Hs
		849492 FBW1A_HUMAN (391-493): 9.75e-13: 72.2: 18.45		UB2D1_HUMAN (4-164): 7.38e-73: 217: 36.65
+	Hs
		919912 FBW1A_HUMAN (391-493): 9.75e-13: 72.2: 18.45		UB2D2_HUMAN (4-164): 1.2e-72: 216: 36.03
+	Hs
		895959 FBW1A_HUMAN (391-493): 9.75e-13: 72.2: 18.45		UB2D3_HUMAN (4-164): 2.23e-71: 213: 36.03
+	Sc
		759317 MET30_YEAST (161-453): 1.2e-10: 65.9: 24.26		UBC7_YEAST (1-165): 1.28e-71: 214: 100.00
+	Hs
		827882 COPA_HUMAN (139-350): 3.58e-20: 96.5: 18.53		UB2R1_HUMAN (4-145): 1.59e-40: 137: 49.30
+	Hs
		863472 COPA_HUMAN (139-350): 3.58e-20: 96.5: 18.53		UB2R2_HUMAN (4-148): 2.6e-40: 137: 47.97
+	Hs
		827995 FBXW7_HUMAN (98-278): 6.53e-15: 79.4: 16.30		UB2R1_HUMAN (4-145): 1.59e-40: 137: 49.30
+	Hs
		1174552 FBW1B_HUMAN (129-286): 3.08e-14: 76.9: 14.29		UB2R2_HUMAN (4-148): 2.6e-40: 137: 47.97
+	Hs
		828051 FBW1B_HUMAN (129-286): 3.08e-14: 76.9: 14.29		UB2R1_HUMAN (4-145): 1.59e-40: 137: 49.30
+	Hs
		1174554 FBW1A_HUMAN (391-493): 9.75e-13: 72.2: 18.45		UB2R2_HUMAN (4-148): 2.6e-40: 137: 47.97
+	Hs
		828061 FBW1A_HUMAN (391-493): 9.75e-13: 72.2: 18.45		UB2R1_HUMAN (4-145): 1.59e-40: 137: 49.30
+	Sc
		539467 MET30_YEAST (161-453): 1.2e-10: 65.9: 24.26		UBC3_YEAST (4-162): 1.54e-35: 126: 41.36