HitPredict

Interactor 1: RPN3 (P40016)
26S proteasome regulatory subunit RPN3
Gene: RPN3

Interactor 2: RPN6 (Q12377)
26S proteasome regulatory subunit RPN6 (Proteasome non-ATPase subunit 4)
Gene: RPN6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 11805826, 12198498, 23911091, 24412063, 9741626, 10873636, 16554755, 16429126, 37968396
Identification Methods tandem affinity purification, pull down, affinity chromatography technology, biochemical
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PCI~PCI, PCI~Rpn3_C, Rpn3_C~RPN6_C_helix
Common GO terms GO:0000502 - proteasome complex
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0008541 - proteasome regulatory particle, lid subcomplex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 523
Sc

1 434
+ Hs
+ Dm
+ Hs
+ Dm
+ Ce
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ At
+ At

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Last updated: 15 Jul 2024