HitPredict

Interactor 1: IMB4 (P40069)
Importin subunit beta-4 (Importin-123) (Karyopherin subunit beta-4) (Karyopherin-123) (Ran-binding protein YRB4)
Gene: KAP123

Interactor 2: H3 (P61830)
Histone H3
Gene: HHT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.857

Property	Details
Experiments	11694505, 17507373, 21179020
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Histone~IBN_N
Common GO terms	GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1113 Sc			1 136
+	Hs
		127242 IPO5_HUMAN (7-1105): 0: 563: 18.50		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		127246 IPO5_HUMAN (7-1105): 0: 563: 18.50		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		127217 IPO5_HUMAN (7-1105): 0: 563: 18.50		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73
+	Sc
		730812 IMB4_YEAST (1-1113): 2.41e-177: 551: 100.00		CENPA_YEAST (24-134): 7.32e-41: 137: 53.04
+	Hs
		935019 IPO4_HUMAN (19-1096): 2.49e-116: 388: 20.18		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		952488 IPO4_HUMAN (19-1096): 2.49e-116: 388: 20.18		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		1086236 IPO4_HUMAN (19-1096): 2.49e-116: 388: 20.18		H31T_HUMAN (1-136): 1.96e-61: 186: 86.03
+	Sc
		687981 IMB3_YEAST (5-1065): 1.11e-110: 372: 17.51		H3_YEAST (1-136): 1.51e-56: 174: 100.00
+	Hs
		828313 IPO4_HUMAN (19-1096): 2.49e-116: 388: 20.18		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73
+	Sc
		687924 IMB3_YEAST (5-1065): 1.11e-110: 372: 17.51		CENPA_YEAST (24-134): 7.32e-41: 137: 53.04
+	Hs
		1060766 IMB1_HUMAN (336-1075): 4.67e-46: 181: 11.11		H31T_HUMAN (1-136): 1.96e-61: 186: 86.03
+	Sc
		730921 IMB1_YEAST (6-696): 1.11e-36: 151: 13.31		CENPA_YEAST (24-134): 7.32e-41: 137: 53.04