Interactor 1: IMB4 (P40069)
Importin subunit beta-4 (Importin-123) (Karyopherin subunit beta-4) (Karyopherin-123) (Ran-binding protein YRB4)
Gene: KAP123

Interactor 2: IMA1 (Q02821)
Importin subunit alpha (Karyopherin subunit alpha) (Karyopherin-60) (Serine-rich RNA polymerase I suppressor protein)
Gene: SRP1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.852

The method score is based on:

Property Details
Experiments 11805837, 16429126, 37968396
Identification Methods anti tag coimmunoprecipitation, affinity chromatography technology, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains IBB~IBN_N
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006606 - protein import into nucleus
GO:0006607 - NLS-bearing protein import into nucleus
GO:0008139 - nuclear localization sequence binding
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1113
Sc

1 542
+ Hs
+ Dm
+ Sc
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ At
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024