HitPredict

Interactor 1: LSM4 (P40070)
U6 snRNA-associated Sm-like protein LSm4 (Like-SM protein 4)
Gene: LSM4

Interactor 2: LSM1 (P47017)
Sm-like protein LSm1 (SPB8 protein)
Gene: LSM1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	1.00	0.979

Property	Details
Experiments	10428970, 10688190, 10747033, 11805826, 16554755, 16429126, 37968396, 17513695, 18719247, 19111170, 22450758
Identification Methods	coimmunoprecipitation, two hybrid, affinity chromatography technology, tandem affinity purification, biochemical
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA GO:0000932 - P-body GO:0005634 - nucleus GO:0005737 - cytoplasm GO:1990726 - Lsm1-7-Pat1 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 187 Sc			1 172
+	Hs
		167728 LSM4_HUMAN (1-98): 5.13e-45: 147: 38.78		LSM1_HUMAN (38-164): 1.07e-33: 117: 36.22
+	Sc
		767810 LSM4_YEAST (1-187): 8.72e-52: 166: 100.00		LSM7_YEAST (8-119): 4.92e-26: 97.5: 27.97
+	Hs
		321444 LSM4_HUMAN (1-98): 5.13e-45: 147: 38.78		LSM8_HUMAN (43-135): 8.57e-29: 104: 32.98
+	Sc
		767791 LSM4_YEAST (1-187): 8.72e-52: 166: 100.00		LSM8_YEAST (43-150): 4.47e-21: 84.7: 18.52
+	Sc
		766909 LSM4_YEAST (1-187): 8.72e-52: 166: 100.00		RSMB_YEAST (35-153): 5.78e-20: 84: 21.32
+	Sc
		767815 LSM4_YEAST (1-187): 8.72e-52: 166: 100.00		LSM3_YEAST (46-120): 1.16e-19: 80.2: 29.87
+	Dm
		1369698 Q9VKW8_DROME (1-127): 2.08e-41: 138: 32.28		Q9W087_DROME (44-136): 1.83e-30: 108: 26.60
+	Sc
		767780 LSM4_YEAST (1-187): 8.72e-52: 166: 100.00		RUXG_YEAST (40-117): 4.06e-19: 78.6: 25.32
+	Hs
		928049 LSM4_HUMAN (1-98): 5.13e-45: 147: 38.78		RSMN_HUMAN (42-118): 8.26e-24: 95.1: 28.24
+	Hs
		539204 LSM4_HUMAN (1-98): 5.13e-45: 147: 38.78		RSMB_HUMAN (42-118): 3e-23: 93.6: 28.24
+	Hs
		1356296 LSM4_HUMAN (1-98): 5.13e-45: 147: 38.78		LSM7_HUMAN (27-117): 7.88e-23: 89: 22.34
+	Hs
		321390 SMD3_HUMAN (2-108): 1.35e-33: 117: 26.17		LSM8_HUMAN (43-135): 8.57e-29: 104: 32.98
+	Dm
		1368675 Q9VKW8_DROME (1-127): 2.08e-41: 138: 32.28		Q9VJI7_DROME (27-119): 5.96e-20: 81.7: 21.65
+	Dm
		218359 SMD3_DROME (2-106): 2.68e-34: 120: 21.70		RSMB_DROME (45-112): 2.65e-23: 92.8: 28.77
+	Dm
		218379 SMD3_DROME (2-106): 2.68e-34: 120: 21.70		RUXG_DROME (41-117): 5.96e-24: 90.9: 28.57
+	Hs
		538896 SMD3_HUMAN (2-108): 1.35e-33: 117: 26.17		RSMB_HUMAN (42-118): 3e-23: 93.6: 28.24
+	Hs
		912024 SMD3_HUMAN (2-108): 1.35e-33: 117: 26.17		RUXG_HUMAN (41-117): 5.65e-24: 90.9: 28.57
+	Ce
		1091044 LSM4_CAEEL (1-95): 3.17e-37: 126: 35.79		Q23543_CAEEL (45-117): 5.72e-20: 81.7: 27.63
+	Dm
		218371 SMD3_DROME (2-106): 2.68e-34: 120: 21.70		Q9VJI7_DROME (27-119): 5.96e-20: 81.7: 21.65
+	Hs
		68411 SMD3_HUMAN (2-108): 1.35e-33: 117: 26.17		RUXGL_HUMAN (41-117): 5.51e-21: 83.2: 27.27