HitPredict

Interactor 1: CAP2 (P40123)
Adenylyl cyclase-associated protein 2 (CAP 2)
Gene: CAP2

Interactor 2: CAP1 (Q01518)
Adenylyl cyclase-associated protein 1 (CAP 1)
Gene: CAP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	1.00	0.877

The method score is based on:

Property	Details
Experiments	8761950, 28514442, 33961781
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	CAP_C~CAP_C
Common GO terms	GO:0000902 - cell morphogenesis GO:0003779 - actin binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0007015 - actin filament organization and 5 others more... GO:0007163 - establishment or maintenance of cell polarity GO:0007165 - signal transduction GO:0007190 - activation of adenylate cyclase activity GO:0008179 - adenylate cyclase binding GO:0019933 - cAMP-mediated signaling
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	477
Hs

1	475

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024