HitPredict

Interactor 1: PSA2 (P40301)
Proteasome subunit alpha type-2 (PROS-Dm25) (Proteasome 25 kDa subunit)
Gene: Prosalpha2

Interactor 2: Q9V3P3 (Q9V3P3)
LD45860p (Proteasome regulator dREG) (Proteasome regulator gamma, isoform A) (Proteasome regulator gamma, isoform B)
Gene: REG

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PA28_beta~Proteasome, PA28_beta~Proteasome_A_N
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 234 Dm			1 245
+	Dm
		1278635 PSA5_DROME (1-233): 1.55e-97: 286: 30.71		Q9V3P3_DROME (1-245): 5.84e-117: 335: 100.00
+	Hs
		656192 PSA5_HUMAN (1-233): 1.45e-98: 288: 31.38		PSME3_HUMAN (7-245): 3.59e-112: 323: 48.76
+	Hs
		637666 PSA2_HUMAN (1-233): 1.3e-95: 280: 78.11		PSME3_HUMAN (7-245): 3.59e-112: 323: 48.76
+	Hs
		637377 PSA1_HUMAN (1-233): 5.72e-92: 272: 30.67		PSME3_HUMAN (7-245): 3.59e-112: 323: 48.76
+	Hs
		156268 PSA7_HUMAN (6-231): 9.41e-91: 268: 36.52		PSME3_HUMAN (7-245): 3.59e-112: 323: 48.76
+	Hs
		656208 PSA5_HUMAN (1-233): 1.45e-98: 288: 31.38		PSME1_HUMAN (8-245): 2.69e-102: 298: 37.40
+	Hs
		656335 PSA5_HUMAN (1-233): 1.45e-98: 288: 31.38		PSME2_HUMAN (8-245): 1.14e-100: 294: 32.77
+	Hs
		637676 PSA2_HUMAN (1-233): 1.3e-95: 280: 78.11		PSME1_HUMAN (8-245): 2.69e-102: 298: 37.40
+	Hs
		637753 PSA2_HUMAN (1-233): 1.3e-95: 280: 78.11		PSME2_HUMAN (8-245): 1.14e-100: 294: 32.77
+	Hs
		637395 PSA1_HUMAN (1-233): 5.72e-92: 272: 30.67		PSME1_HUMAN (8-245): 2.69e-102: 298: 37.40
+	Hs
		893656 PSA6_HUMAN (3-233): 6.35e-91: 269: 32.49		PSME1_HUMAN (8-245): 2.69e-102: 298: 37.40
+	Hs
		156276 PSA7_HUMAN (6-231): 9.41e-91: 268: 36.52		PSME1_HUMAN (8-245): 2.69e-102: 298: 37.40
+	Hs
		637601 PSA1_HUMAN (1-233): 5.72e-92: 272: 30.67		PSME2_HUMAN (8-245): 1.14e-100: 294: 32.77
+	Hs
		156373 PSA7_HUMAN (6-231): 9.41e-91: 268: 36.52		PSME2_HUMAN (8-245): 1.14e-100: 294: 32.77
+	Dm
		611651 PSA71_DROME (3-230): 2.89e-44: 150: 36.48		Q9V3P3_DROME (1-245): 5.84e-117: 335: 100.00
+	Hs
		898972 PSMA8_HUMAN (5-216): 1.1e-47: 159: 40.27		PSME3_HUMAN (7-245): 3.59e-112: 323: 48.76
+	Hs
		638103 PSA4_HUMAN (3-217): 3.05e-44: 150: 39.64		PSME3_HUMAN (7-245): 3.59e-112: 323: 48.76
+	Hs
		638116 PSA4_HUMAN (3-217): 3.05e-44: 150: 39.64		PSME1_HUMAN (8-245): 2.69e-102: 298: 37.40
+	Hs
		638215 PSA4_HUMAN (3-217): 3.05e-44: 150: 39.64		PSME2_HUMAN (8-245): 1.14e-100: 294: 32.77