Protein: ITB2
Integrin beta-2 (Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD antigen CD18)

Gene: ITB2, Itgb2
Organism: Mus musculus
Interactions: 66
UniProt ID: P11835

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0001851 - complement component C3b binding
GO:0002523 - leukocyte migration involved in inflammatory response
GO:0005178 - integrin binding
GO:0005925 - focal adhesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

93610

E9Q604
Integrin alpha M

1

20

High-throughput

0.647

High

515639

ITB2
Integrin beta-2

1

14

High-throughput

0.647

High

515662

FLNB
Filamin-B

1

20

High-throughput

0.647

High

515666

FLNA
Filamin-A

1

20

High-throughput

0.647

High

515643

ITAL
Integrin alpha-L

1

20

Small-scale

0.618

High

515676

FLNC
Filamin-C

1

20

High-throughput

0.579

High

57456

UBR4
E3 ubiquitin-protein ligase UBR4

1

2

High-throughput

0.501

High

93759

HELZ2
3'-5' exoribonuclease HELZ2

1

7

High-throughput

0.501

High

101833

F8WIE5
E3 ubiquitin-protein ligase

1

15

High-throughput

0.501

High

292201

BIRC6
Baculoviral IAP repeat-containing protein 6

1

3

High-throughput

0.501

High

344737

CO3
Complement C3

1

2

High-throughput

0.501

High

515640

MAP1B
Microtubule-associated protein 1B

1

5

High-throughput

0.501

High

515641

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

1

High-throughput

0.501

High

515644

TLN1
Talin-1

1

20

High-throughput

0.501

High

515649

WNK1
Serine/threonine-protein kinase WNK1

1

8

High-throughput

0.501

High

515654

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

19

High-throughput

0.501

High

515656

MYOF
Myoferlin

1

5

High-throughput

0.501

High

515658

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

4

High-throughput

0.501

High

515663

LIMD2
LIM domain-containing protein 2

1

4

High-throughput

0.501

High

515672

PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

1

2

High-throughput

0.501

High

515690

PLEC
Plectin

1

13

High-throughput

0.501

High

515691

DREB
Drebrin

1

8

High-throughput

0.501

High

515652

STING
Stimulator of interferon genes protein

1

2

High-throughput

0.479

High

515680

1433B
14-3-3 protein beta/alpha

1

4

Small-scale

0.479

High

515688

LRP1B
Low-density lipoprotein receptor-related protein 1B

1

7

Small-scale

0.479

High

515653

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

0

High-throughput

0.458

High

57006

SPD2B
SH3 and PX domain-containing protein 2B

1

3

High-throughput

0.457

High

57478

A2ANY6
Midasin

1

12

High-throughput

0.457

High

69895

UBP24
Ubiquitin carboxyl-terminal hydrolase 24

1

8

High-throughput

0.457

High

82747

B9EKJ1
Spna2 protein

1

19

High-throughput

0.457

High

100196

TPR
Nucleoprotein TPR

1

9

High-throughput

0.457

High

102758

G3X9H5
Huntingtin

1

3

High-throughput

0.457

High

515645

RADI
Radixin

1

7

High-throughput

0.457

High

515646

UBA1Y
Ubiquitin-like modifier-activating enzyme 1 Y

1

2

High-throughput

0.457

High

515648

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

7

High-throughput

0.457

High

515655

Q68FM7
Rho guanine nucleotide exchange factor

1

7

High-throughput

0.457

High

515657

NOMO1
BOS complex subunit NOMO1

1

1

High-throughput

0.457

High

515659

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

12

High-throughput

0.457

High

515661

UBP2L
Ubiquitin-associated protein 2-like

1

1

High-throughput

0.457

High

515664

Q8BIX2
GCN1 activator of EIF2AK4

1

11

High-throughput

0.457

High

515665

SRRM2
Serine/arginine repetitive matrix protein 2

1

6

High-throughput

0.457

High

515668

TAOK3
Serine/threonine-protein kinase TAO3

1

3

High-throughput

0.457

High

515669

SMC4
Structural maintenance of chromosomes protein 4

1

8

High-throughput

0.457

High

515670

SMC2
Structural maintenance of chromosomes protein 2

1

8

High-throughput

0.457

High

515671

TCRG1
Transcription elongation regulator 1

1

2

High-throughput

0.457

High

515673

IPO11
Importin-11

1

12

High-throughput

0.457

High

515674

SF3A1
Splicing factor 3A subunit 1

1

5

High-throughput

0.457

High

515675

PSPC1
Paraspeckle component 1

1

2

High-throughput

0.457

High

515677

PECR
Peroxisomal trans-2-enoyl-CoA reductase

1

2

High-throughput

0.457

High

515685

XPO7
Exportin-7

1

5

High-throughput

0.457

High

515687

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

7

High-throughput

0.457

High

515689

SON
Protein SON

1

10

High-throughput

0.457

High

515642

CBL
E3 ubiquitin-protein ligase CBL

1

4

High-throughput

0.445

High

515684

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit [Cleaved into: cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed]

1

2

High-throughput

0.417

High

515647

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.261

Low

515650

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.261

Low

515667

UTP25
U3 small nucleolar RNA-associated protein 25 homolog

1

0

High-throughput

0.261

Low

515678

LGUL
Lactoylglutathione lyase

1

0

High-throughput

0.261

Low

515679

ARPC5
Actin-related protein 2/3 complex subunit 5

1

0

High-throughput

0.261

Low

515681

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.261

Low

515682

NOP56
Nucleolar protein 56

1

0

High-throughput

0.261

Low

515683

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.261

Low

515686

CLPX
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial

1

0

High-throughput

0.261

Low

515660

FACD2
Fanconi anemia group D2 protein homolog

1

0

High-throughput

0.249

Low

515651

S39A7
Zinc transporter SLC39A7

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024