Interactor 1: PSA4 (P40303)
Proteasome subunit alpha type-4 (Macropain subunit PRE6) (Multicatalytic endopeptidase complex subunit PRE6) (Proteasome component PRE6) (Proteinase YSCE subunit PRE6)
Gene: PRE6

Interactor 2: RPN11 (P43588)
Ubiquitin carboxyl-terminal hydrolase RPN11 (EC 3.4.19.12) (26S proteasome regulatory subunit RPN11) (Protein MPR1)
Gene: RPN11

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.751

The method score is based on:

Property Details
Experiments 22037170, 16284124, 22215586, 24038880, 37968396, 15917626, 21321079, 21627799, 21658604, 22927375
Identification Methods pull down, affinity chromatography technology, biochemical
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0034515 - proteasome storage granule
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 254
Sc

1 306
+ Dm
+ Hs
+ Hs
+ Hs
+ Sp
+ Hs
+ Hs
+ Sp
+ Sp
+ Hs
+ Hs
+ Hs
+ Sc
+ Dm
+ Dm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024