Interactor 1: SECU (P40316)
Securin
Gene: PDS1

Interactor 2: ESP1 (Q03018)
Separin (EC 3.4.22.49) (Separase)
Gene: ESP1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.90 0.930

The method score is based on:

Property Details
Experiments 12050115, 9635435, 11433293, 27418100, 32402080, 11149918, 12123570, 28146474, 25822502, 29561844, 18719252, 32591482
Identification Methods coimmunoprecipitation, affinity chromatography technology, protein complementation assay, pull down, x-ray crystallography, two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Peptidase_C50~Securin
Common GO terms GO:0000070 - mitotic sister chromatid segregation
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005819 - spindle
GO:1902104 - positive regulation of metaphase/anaphase transition of meiotic cell cycle
and 1 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024