Protein: PROP
Properdin (Complement factor P)

Gene: PROP, CFP
Organism: Homo sapiens
Interactions: 50
UniProt ID: P27918

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005788 - endoplasmic reticulum lumen
GO:0006955 - immune response
GO:0006956 - complement activation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

369836

CO3
Complement C3

2

2

Small-scale

0.778

High

366571

CFAB
Complement factor B

1

7

Small-scale

0.647

High

699459

ATL4
ADAMTS-like protein 4

1

9

High-throughput

0.590

High

699460

B3GLT
Beta-1,3-glucosyltransferase

2

6

High-throughput

0.574

High

699461

D19L3
Protein C-mannosyl-transferase DPY19L3

2

5

High-throughput

0.574

High

699475

CRAC1
Cartilage acidic protein 1

2

10

High-throughput

0.574

High

276673

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

2

1

High-throughput

0.561

High

70124

CRTP1
Cysteine-rich tail protein 1

2

3

High-throughput

0.553

High

225538

AAKB2
5'-AMP-activated protein kinase subunit beta-2

2

1

High-throughput

0.553

High

291754

STK16
Serine/threonine-protein kinase 16

2

7

High-throughput

0.553

High

330049

VENTX
Homeobox protein VENTX

2

3

High-throughput

0.553

High

699447

HXA1
Homeobox protein Hox-A1

2

5

High-throughput

0.553

High

699449

KR122
Keratin-associated protein 12-2

2

20

High-throughput

0.553

High

699452

LONF1
LON peptidase N-terminal domain and RING finger protein 1

2

4

High-throughput

0.553

High

699453

KLH38
Kelch-like protein 38

2

1

High-throughput

0.553

High

699454

KRA62
Keratin-associated protein 6-2

2

1

High-throughput

0.553

High

699455

LCE1A
Late cornified envelope protein 1A

2

1

High-throughput

0.553

High

699456

FHL5
Four and a half LIM domains protein 5

2

5

High-throughput

0.553

High

699462

KCTD9
BTB/POZ domain-containing protein KCTD9

2

5

High-throughput

0.553

High

699465

CF206
Cilia- and flagella-associated protein 206

2

1

High-throughput

0.553

High

699467

SMRC1
SWI/SNF complex subunit SMARCC1

2

2

High-throughput

0.553

High

699468

ZN414
Zinc finger protein 414

2

1

High-throughput

0.553

High

699469

HEXI2
Protein HEXIM2

2

1

High-throughput

0.553

High

699472

KRA31
Keratin-associated protein 3-1

2

1

High-throughput

0.553

High

699473

BAFL
Barrier-to-autointegration factor-like protein

2

1

High-throughput

0.553

High

699474

NEK6
Serine/threonine-protein kinase Nek6

2

10

High-throughput

0.553

High

699476

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

8

High-throughput

0.553

High

699477

GLCNE
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

2

1

High-throughput

0.553

High

699478

ZN330
Zinc finger protein 330

2

1

High-throughput

0.553

High

302018

NCTR1
Natural cytotoxicity triggering receptor 1

1

1

Small-scale

0.512

High

469413

ELNE
Neutrophil elastase

1

18

Small-scale

0.501

High

469776

CATG
Cathepsin G

1

12

Small-scale

0.501

High

528195

THIO
Thioredoxin

1

2

Small-scale

0.501

High

628604

CAP7
Azurocidin

1

15

Small-scale

0.501

High

664030

PRTN3
Myeloblastin

1

16

Small-scale

0.501

High

699450

LYSC
Lysozyme C

1

2

Small-scale

0.501

High

352004

RECK
Reversion-inducing cysteine-rich protein with Kazal motifs

1

1

High-throughput

0.481

High

425710

PERM
Myeloperoxidase

1

0

Small-scale

0.480

High

699458

Q6P9E2
RECK protein

1

1

High-throughput

0.470

High

699446

MTOR
Serine/threonine-protein kinase mTOR

1

1

Small-scale

0.457

High

699451

PCH2
Pachytene checkpoint protein 2 homolog

1

4

High-throughput

0.439

High

277275

PITX3
Pituitary homeobox 3

1

1

Small-scale

0.437

High

699466

ESR2
Estrogen receptor beta

1

6

High-throughput

0.437

High

699470

CRBN
Protein cereblon

2

0

High-throughput

0.328

High

699471

SPAG8
Sperm-associated antigen 8

2

0

High-throughput

0.320

High

699448

GEMI4
Gem-associated protein 4

2

0

High-throughput

0.316

High

699463

NOXA1
NADPH oxidase activator 1

2

0

High-throughput

0.316

High

699464

KR111
Keratin-associated protein 11-1

2

0

High-throughput

0.316

High

699479

SNX8
Sorting nexin-8

1

0

High-throughput

0.279

Low

699457

OTU1
Ubiquitin thioesterase OTU1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025