Interactor 1: THI6 (P40386)
Probable thiamine biosynthetic bifunctional enzyme [Includes: Thiamine-phosphate synthase (TP synthase) (TPS) (EC 2.5.1.3) (Thiamine-phosphate pyrophosphorylase) (TMP pyrophosphorylase) (TMP-PPase); Hydroxyethylthiazole kinase (EC 2.7.1.50) (4-methyl-5-beta-hydroxyethylthiazole kinase) (TH kinase) (THZ kinase)]
Gene: thi4

Interactor 2: THI6 (P40386)
Probable thiamine biosynthetic bifunctional enzyme [Includes: Thiamine-phosphate synthase (TP synthase) (TPS) (EC 2.5.1.3) (Thiamine-phosphate pyrophosphorylase) (TMP pyrophosphorylase) (TMP-PPase); Hydroxyethylthiazole kinase (EC 2.7.1.50) (4-methyl-5-beta-hydroxyethylthiazole kinase) (TH kinase) (THZ kinase)]
Gene: thi4

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 26771498
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HK~HK, HK~TMP-TENI, TMP-TENI~TMP-TENI
Common GO terms GO:0000287 - magnesium ion binding
GO:0004417 - hydroxyethylthiazole kinase activity
GO:0004789 - thiamine-phosphate diphosphorylase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
and 4 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 518
Sp

1 518
+ Sc
+ Hp
+ Cj

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Last updated: 15 Jul 2024