HitPredict

Interactor 1: TCPE (P40413)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon)
Gene: CCT5

Interactor 2: CMR1 (Q12510)
DNA damage-binding protein CMR1 (Changed mutation rate protein 1)
Gene: CMR1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	25817432, 22199229
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 562 Sc			1 522
+	Hs
		821337 TCPE_HUMAN (16-561): 0: 589: 59.89		DDB2_HUMAN (186-519): 2.35e-110: 336: 17.71
+	Hs
		1265890 TCPH_HUMAN (25-560): 0: 561: 29.66		DDB2_HUMAN (186-519): 2.35e-110: 336: 17.71
+	Hs
		821413 TCPE_HUMAN (16-561): 0: 589: 59.89		WDR76_HUMAN (4-515): 2.47e-92: 296: 22.98
+	Hs
		1306687 TCPH_HUMAN (25-560): 0: 561: 29.66		WDR76_HUMAN (4-515): 2.47e-92: 296: 22.98
+	Hs
		821326 TCPE_HUMAN (16-561): 0: 589: 59.89		POC1B_HUMAN (283-521): 7.24e-54: 190: 12.81
+	Hs
		1202777 TCPH_HUMAN (25-560): 0: 561: 29.66		WDR5B_HUMAN (114-471): 1.6e-59: 201: 12.06
+	Hs
		821152 TCPE_HUMAN (16-561): 0: 589: 59.89		WDR5_HUMAN (365-520): 1.09e-35: 137: 13.29
+	Hs
		821355 TCPE_HUMAN (16-561): 0: 589: 59.89		SNR40_HUMAN (382-520): 4.44e-28: 117: 14.79
+	Hs
		792942 TCPG_HUMAN (25-561): 0: 554: 30.13		LIS1_HUMAN (329-521): 1.15e-38: 147: 13.33
+	Hs
		903467 TCPH_HUMAN (25-560): 0: 561: 29.66		WDR5_HUMAN (365-520): 1.09e-35: 137: 13.29
+	Hs
		821316 TCPE_HUMAN (16-561): 0: 589: 59.89		POC1A_HUMAN (378-511): 7.24e-25: 108: 11.68
+	Hs
		821387 TCPE_HUMAN (16-561): 0: 589: 59.89		TBL1Y_HUMAN (363-521): 3.05e-24: 107: 11.73
+	Hs
		821190 TCPE_HUMAN (16-561): 0: 589: 59.89		ERCC8_HUMAN (180-513): 8.25e-24: 105: 14.66
+	Hs
		826601 TCPG_HUMAN (25-561): 0: 554: 30.13		WDR5_HUMAN (365-520): 1.09e-35: 137: 13.29
+	Hs
		821437 TCPE_HUMAN (16-561): 0: 589: 59.89		NLE1_HUMAN (442-519): 3.67e-19: 92.4: 17.50
+	Hs
		1240450 TCPH_HUMAN (25-560): 0: 561: 29.66		POC1A_HUMAN (378-511): 7.24e-25: 108: 11.68
+	Hs
		1306645 TCPH_HUMAN (25-560): 0: 561: 29.66		TBL1Y_HUMAN (363-521): 3.05e-24: 107: 11.73
+	Hs
		1028020 TCPH_HUMAN (25-560): 0: 561: 29.66		ERCC8_HUMAN (180-513): 8.25e-24: 105: 14.66
+	At
		138361 TCPE_ARATH (20-562): 0: 576: 55.99		PEX7_ARATH (184-430): 3.39e-18: 87.3: 17.67
+	Hs
		1306704 TCPH_HUMAN (25-560): 0: 561: 29.66		NLE1_HUMAN (442-519): 3.67e-19: 92.4: 17.50