Protein: STON2
Stonin-2 (Stoned B)

Gene: STON2
Organism: Homo sapiens
Interactions: 86
UniProt ID: Q8WXE9

Gene Ontology (top 5):
GO:0005730 - nucleolus
GO:0005829 - cytosol
GO:0008021 - synaptic vesicle
GO:0030100 - regulation of endocytosis
GO:0030122 - AP-2 adaptor complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

839804

EPS15
Epidermal growth factor receptor substrate 15

5

14

Small-scale

0.946

High

1360366

AP2M1
AP-2 complex subunit mu

5

11

Small-scale

0.924

High

922598

AP2S1
AP-2 complex subunit sigma

3

19

High-throughput

0.855

High

1360380

EP15R
Epidermal growth factor receptor substrate 15-like 1

3

15

Small-scale

0.854

High

989065

AP2B1
AP-2 complex subunit beta

2

20

High-throughput

0.789

High

1154145

ITSN1
Intersectin-1

1

10

Small-scale

0.740

High

1083288

AP1B1
AP-1 complex subunit beta-1

1

20

High-throughput

0.691

High

1360367

REPS1
RalBP1-associated Eps domain-containing protein 1

1

17

Small-scale

0.647

High

639153

SYT1
Synaptotagmin-1

3

4

Small-scale

0.646

High

1129845

EPN4
Clathrin interactor 1

2

5

High-throughput

0.628

High

159769

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

5

High-throughput

0.618

High

1360378

ANLN
Anillin

2

2

High-throughput

0.611

High

1328434

S2541
Mitochondrial carrier protein SCaMC-3L

3

4

High-throughput

0.609

High

1145302

RNPS1
RNA-binding protein with serine-rich domain 1

2

1

High-throughput

0.601

High

375781

RASK
GTPase KRas

2

7

High-throughput

0.584

High

978200

RHOB
Rho-related GTP-binding protein RhoB

2

13

High-throughput

0.584

High

1360375

EHD1
EH domain-containing protein 1

1

15

Small-scale

0.579

High

1331826

SYT2
Synaptotagmin-2

2

4

Small-scale

0.565

High

619871

VCAM1
Vascular cell adhesion protein 1

2

2

High-throughput

0.549

High

171741

GAK
Cyclin-G-associated kinase

1

7

High-throughput

0.536

High

483375

CLCB
Clathrin light chain B

1

5

High-throughput

0.536

High

637658

FLNA
Filamin-A

1

2

High-throughput

0.536

High

765741

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.536

High

772928

MYH9
Myosin-9

1

1

High-throughput

0.536

High

866768

CAZA2
F-actin-capping protein subunit alpha-2

1

1

High-throughput

0.536

High

968394

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

1

High-throughput

0.536

High

1026151

CLH1
Clathrin heavy chain 1

1

4

High-throughput

0.536

High

1107587

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

1

High-throughput

0.536

High

1115855

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

3

High-throughput

0.536

High

1325427

SYNPO
Synaptopodin

1

3

High-throughput

0.536

High

1360368

MYO19
Unconventional myosin-XIX

1

4

High-throughput

0.536

High

1360373

RGAP1
Rac GTPase-activating protein 1

1

2

High-throughput

0.536

High

1360379

GTSE1
G2 and S phase-expressed protein 1

1

2

High-throughput

0.536

High

1360382

LIMA1
LIM domain and actin-binding protein 1

1

3

High-throughput

0.536

High

508347

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

8

High-throughput

0.501

High

1154881

NEDD8
Ubiquitin-like protein NEDD8

1

3

Small-scale

0.500

High

389453

FINC
Fibronectin

1

1

High-throughput

0.489

High

1160705

DREB
Drebrin

1

3

High-throughput

0.489

High

1348928

ZCH10
Zinc finger CCHC domain-containing protein 10

1

1

High-throughput

0.489

High

1360363

MY18A
Unconventional myosin-XVIIIa

1

3

High-throughput

0.489

High

1360370

CCD32
Coiled-coil domain-containing protein 32

1

1

High-throughput

0.489

High

1360371

WNK3
Serine/threonine-protein kinase WNK3

1

3

High-throughput

0.489

High

126721

RHOD
Rho-related GTP-binding protein RhoD

1

17

High-throughput

0.479

High

160734

TOR1A
Torsin-1A

1

2

Small-scale

0.479

High

189744

STX7
Syntaxin-7

1

1

High-throughput

0.479

High

223217

PRC1
Protein regulator of cytokinesis 1

1

5

High-throughput

0.479

High

362330

ABL1
Tyrosine-protein kinase ABL1

1

4

High-throughput

0.479

High

372697

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.479

High

401213

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.479

High

466387

RHOC
Rho-related GTP-binding protein RhoC

1

12

High-throughput

0.479

High

483169

CLCA
Clathrin light chain A

1

5

High-throughput

0.479

High

535350

BIP
Endoplasmic reticulum chaperone BiP

1

9

High-throughput

0.479

High

581200

RAC2
Ras-related C3 botulinum toxin substrate 2

1

10

High-throughput

0.479

High

900058

FXR1
RNA-binding protein FXR1

1

6

High-throughput

0.479

High

942779

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

4

High-throughput

0.479

High

953592

RAC3
Ras-related C3 botulinum toxin substrate 3

1

12

High-throughput

0.479

High

955423

CDC42
Cell division control protein 42 homolog

1

13

High-throughput

0.479

High

962324

RHOA
Transforming protein RhoA

1

13

High-throughput

0.479

High

988567

RAC1
Ras-related C3 botulinum toxin substrate 1

1

12

High-throughput

0.479

High

1015636

RHOG
Rho-related GTP-binding protein RhoG

1

10

High-throughput

0.479

High

1067543

EP300
Histone acetyltransferase p300

1

4

High-throughput

0.479

High

1140622

KIF14
Kinesin-like protein KIF14

1

4

High-throughput

0.479

High

1178780

AAK1
AP2-associated protein kinase 1

1

11

High-throughput

0.479

High

1270926

RHOU
Rho-related GTP-binding protein RhoU

1

13

High-throughput

0.479

High

1360369

CSN4
COP9 signalosome complex subunit 4

1

1

Small-scale

0.479

High

1360372

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.479

High

1360376

RHOF
Rho-related GTP-binding protein RhoF

1

15

High-throughput

0.479

High

1360381

HDAC6
Protein deacetylase HDAC6

1

2

High-throughput

0.479

High

1360377

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.458

High

72387

A9UF07
Tyrosine-protein kinase ABL1

1

6

High-throughput

0.445

High

934916

TERA
Transitional endoplasmic reticulum ATPase

1

4

High-throughput

0.445

High

218549

TGON2
Trans-Golgi network integral membrane protein 2

1

7

High-throughput

0.437

High

315818

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.437

High

565431

ITA4
Integrin alpha-4

1

1

High-throughput

0.437

High

1024727

VIGLN
Vigilin

1

3

High-throughput

0.437

High

1233388

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.437

High

1254836

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

1258352

MOB3C
MOB kinase activator 3C

1

1

High-throughput

0.437

High

1276251

ATG9A
Autophagy-related protein 9A

1

6

High-throughput

0.437

High

1360364

ESR2
Estrogen receptor beta

1

7

High-throughput

0.437

High

1360374

RHOJ
Rho-related GTP-binding protein RhoJ

1

14

High-throughput

0.437

High

255139

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

1

High-throughput

0.407

High

430172

JUN
Transcription factor Jun

1

4

High-throughput

0.407

High

1293272

LSR
Lipolysis-stimulated lipoprotein receptor

2

0

High-throughput

0.328

High

418306

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

1360365

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025