HitPredict

Interactor 1: YIA1 (P40560)
Ankyrin repeat-containing protein YIL001W
Gene: YIL001W

Interactor 2: CUL3 (P53202)
Cullin-3 (Cullin-B)
Gene: CUL3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	37968396, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BTB~Cullin
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 513 Sc			1 744
+	Hs
		1042221 ABTB1_HUMAN (13-512): 3.98e-82: 264: 23.66		CUL3_HUMAN (2-744): 0: 741: 24.30
+	Hs
		1041780 BTBD8_HUMAN (96-509): 5.82e-64: 227: 16.74		CUL3_HUMAN (2-744): 0: 741: 24.30
+	Hs
		1042047 ABTB2_HUMAN (2-463): 6.81e-64: 226: 14.42		CUL3_HUMAN (2-744): 0: 741: 24.30
+	Hs
		1042716 IBTK_HUMAN (78-447): 6.83e-63: 224: 17.02		CUL3_HUMAN (2-744): 0: 741: 24.30
+	Mm
		1169620 IBTK_MOUSE (78-445): 1.89e-62: 223: 17.49		CUL3_MOUSE (2-744): 0: 740: 24.17
+	Hs
		1042881 KLH20_HUMAN (226-511): 3.31e-62: 215: 11.50		CUL3_HUMAN (2-744): 0: 741: 24.30
+	Hs
		1043281 KLHL3_HUMAN (228-511): 3.12e-57: 202: 9.83		CUL4A_HUMAN (4-744): 0: 751: 22.38
+	Hs
		64280 ABTB3_HUMAN (3-440): 1.86e-58: 211: 13.97		CUL3_HUMAN (2-744): 0: 741: 24.30
+	Hs
		1042057 KLH23_HUMAN (250-513): 1.17e-57: 202: 15.09		CUL3_HUMAN (2-744): 0: 741: 24.30
+	Hs
		1042768 KLHL3_HUMAN (228-511): 3.12e-57: 202: 9.83		CUL3_HUMAN (2-744): 0: 741: 24.30
+	Mm
		1225041 KLHL2_MOUSE (229-511): 3.29e-57: 202: 9.51		CUL3_MOUSE (2-744): 0: 740: 24.17
+	Hs
		1041712 KLH12_HUMAN (246-511): 7.04e-57: 200: 14.61		CUL3_HUMAN (2-744): 0: 741: 24.30
+	Hs
		307170 KLHL2_HUMAN (229-511): 9.27e-57: 200: 9.16		CUL3_HUMAN (2-744): 0: 741: 24.30
+	Hs
		1043391 KLH12_HUMAN (246-511): 7.04e-57: 200: 14.61		CUL4B_HUMAN (3-744): 0: 740: 22.62
+	Rn
		78189 KLH17_RAT (236-511): 4.79e-56: 199: 11.55		CUL3_RAT (2-744): 0: 741: 24.30
+	Dm
		1213852 KLHDB_DROME (244-511): 1.22e-58: 206: 13.38		Q8IP45_DROME (10-744): 0: 715: 24.07
+	Dm
		980063 KELC_DROME (228-511): 5.4e-55: 201: 12.28		Q8IP45_DROME (10-744): 0: 715: 24.07
+	Hs
		1041022 KLH12_HUMAN (246-511): 7.04e-57: 200: 14.61		CUL1_HUMAN (8-744): 0: 710: 19.42
+	Rn
		70072 KLH17_RAT (236-511): 4.79e-56: 199: 11.55		B1WBY1_RAT (10-744): 0: 709: 19.47
+	Sp
		999887 BTB3_SCHPO (13-511): 1.64e-78: 256: 32.94		CUL3_SCHPO (1-744): 0: 610: 24.16