HitPredict

Interactor 1: MSL1 (P40567)
U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'')
Gene: MSL1

Interactor 2: CWC2 (Q12046)
Pre-mRNA-splicing factor CWC2 (Complexed with CEF1 protein 2) (PRP19-associated complex protein 40) (Synthetic lethal with CLF1 protein 3)
Gene: CWC2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	11884590, 14690591
Identification Methods	affinity chromatography technology, tandem affinity purification, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_5
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 111 Sc			1 339
+	Hs
		1347098 PPIE_HUMAN (27-105): 2.02e-23: 93: 26.51		RBM22_HUMAN (5-253): 3.12e-81: 254: 20.93
+	Sp
		953364 YDC1_SCHPO (2-109): 1.7e-25: 98.3: 25.00		CWC2_SCHPO (7-302): 1.19e-76: 242: 35.64
+	Sp
		953367 RU2B_SCHPO (28-111): 1.1e-25: 94: 40.00		CWC2_SCHPO (7-302): 1.19e-76: 242: 35.64
+	Hs
		446810 SNRPA_HUMAN (2-106): 3.28e-12: 62.4: 18.52		RBM22_HUMAN (5-253): 3.12e-81: 254: 20.93
+	Hs
		1054618 RBM39_HUMAN (4-109): 9.05e-12: 61.7: 26.36		RBM22_HUMAN (5-253): 3.12e-81: 254: 20.93
+	Hs
		441380 RU2B_HUMAN (3-106): 2.3e-11: 59.7: 18.52		RBM22_HUMAN (5-253): 3.12e-81: 254: 20.93
+	Dm
		1361600 Q9VAX3_DROME (30-109): 9.61e-21: 87.5: 20.24		Q9VAX3_DROME (28-239): 2.14e-13: 72.6: 16.06
+	Hs
		963504 TIAR_HUMAN (22-108): 1.27e-16: 75.1: 21.35		TIAR_HUMAN (7-257): 5.64e-14: 74.1: 15.83
+	Hs
		446592 SNRPA_HUMAN (2-106): 3.28e-12: 62.4: 18.52		TIAR_HUMAN (7-257): 5.64e-14: 74.1: 15.83
+	Hs
		165475 RBM39_HUMAN (4-109): 9.05e-12: 61.7: 26.36		SR140_HUMAN (123-296): 1.8e-12: 70.3: 18.56
+	Hs
		165379 RU2B_HUMAN (3-106): 2.3e-11: 59.7: 18.52		SR140_HUMAN (123-296): 1.8e-12: 70.3: 18.56