HitPredict

Interactor 1: STAT3 (P40763)
Signal transducer and activator of transcription 3 (Acute-phase response factor)
Gene: STAT3

Interactor 2: LRC32 (Q14392)
Transforming growth factor beta activator LRRC32 (Garpin) (Glycoprotein A repetitions predominant) (GARP) (Leucine-rich repeat-containing protein 32)
Gene: LRRC32

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_8~SH2
Common GO terms GO:0005654 - nucleoplasm
GO:0005886 - plasma membrane
GO:0007179 - transforming growth factor beta receptor signaling pathway
GO:0010628 - positive regulation of gene expression
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 770
Hs

1 662
+ Hs

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Last updated: 15 Jul 2024