HitPredict

Interactor 1: NOP2 (P40991)
25S rRNA (cytosine(2870)-C(5))-methyltransferase (EC 2.1.1.310) (Nucleolar protein 2)
Gene: NOP2

Interactor 2: ERB1 (Q04660)
Ribosome biogenesis protein ERB1 (Eukaryotic ribosome biogenesis protein 1)
Gene: ERB1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.732

The method score is based on:

Property Details
Experiments 11805837, 11805826, 16429126, 37968396, 34686661, 37811893
Identification Methods anti tag coimmunoprecipitation, tandem affinity purification, affinity chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0030687 - preribosome, large subunit precursor
and 1 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 618
Sc

1 807
+ Sc
+ Sc
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024