Interactor 1: CENPA (P36012)
Histone H3-like centromeric protein CSE4 (CENP-A homolog) (CENPA homolog) (Chromosome segregation protein 4)
Gene: CSE4

Interactor 2: SCM3 (Q12334)
Protein SCM3 (Suppressor of chromosome missegregation protein 3)
Gene: SCM3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.984

The method score is based on:

Property Details
Experiments 17548816, 17574026, 17634282, 28980861, 39809842, 21816344, 24623811, 25833709, 17569568, 32111629, 34217622, 38565139, 21412236, 21980305, 21179020
Identification Methods pull down, two hybrid, affinity chromatography technology, x-ray crystallography, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Histone~Scm3
Common GO terms GO:0000779 - condensed chromosome, centromeric region
GO:0005634 - nucleus
GO:0051382 - kinetochore assembly
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 229
Sc

1 223
+ Sc
+ Kl

Service provided by Combinatics, Japan

Last updated: 11Aug2025