Interactor 1: CENPA (P36012)
Histone H3-like centromeric protein CSE4 (CENP-A homolog) (CENPA homolog) (Chromosome segregation protein 4)
Gene: CSE4
Interactor 2: SCM3 (Q12334)
Protein SCM3 (Suppressor of chromosome missegregation protein 3)
Gene: SCM3
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.984 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17548816, 17574026, 17634282, 28980861, 39809842, 21816344, 24623811, 25833709, 17569568, 32111629, 34217622, 38565139, 21412236, 21980305, 21179020 |
| Identification Methods | pull down, two hybrid, affinity chromatography technology, x-ray crystallography, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Histone~Scm3 |
| Common GO terms | GO:0000779 - condensed chromosome, centromeric region GO:0005634 - nucleus GO:0051382 - kinetochore assembly |
| Homologous interactions | 2 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025