HitPredict

Interactor 1: CCNF (P41002)
Cyclin-F (F-box only protein 1)
Gene: CCNF

Interactor 2: PKN2 (Q16513)
Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2)
Gene: PKN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36114006
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cyclin_C~Pkinase, Cyclin_N~Pkinase
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol GO:0048471 - perinuclear region of cytoplasm and 1 others more... GO:0051301 - cell division
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 786 Hs			1 984
+	Hs
		779490 CCNF_HUMAN (1-786): 0: 952: 100.00		PKN1_HUMAN (15-984): 0: 940: 56.24
+	Hs
		538556 CCNB1_HUMAN (130-537): 8.12e-120: 369: 19.00		PKN2_HUMAN (1-984): 0: 1145: 97.99
+	Hs
		779057 CCNF_HUMAN (1-786): 0: 952: 100.00		KS6A3_HUMAN (442-929): 3.75e-111: 362: 22.16
+	Hs
		779613 CCNF_HUMAN (1-786): 0: 952: 100.00		PKN3_HUMAN (12-215): 6.12e-17: 88.2: 20.69
+	Hs
		682145 CCNF_HUMAN (1-786): 0: 952: 100.00		AKT2_HUMAN (364-610): 4.79e-17: 87.5: 10.84
+	Hs
		681708 CCNF_HUMAN (1-786): 0: 952: 100.00		AKT1_HUMAN (397-605): 8.1e-17: 86.7: 10.70
+	Hs
		590134 CCNA2_HUMAN (141-536): 3.28e-99: 315: 22.28		AKT2_HUMAN (364-610): 4.79e-17: 87.5: 10.84
+	Hs
		590133 CCNA2_HUMAN (141-536): 3.28e-99: 315: 22.28		AKT1_HUMAN (397-605): 8.1e-17: 86.7: 10.70
+	Hs
		590239 CCNA2_HUMAN (141-536): 3.28e-99: 315: 22.28		AKT3_HUMAN (397-574): 3.17e-16: 84.8: 11.17
+	Hs
		590168 CCNA2_HUMAN (141-536): 3.28e-99: 315: 22.28		KPCT_HUMAN (397-567): 7.7e-15: 80.9: 13.37
+	Hs
		624550 CCNE1_HUMAN (177-567): 1.06e-93: 300: 16.14		AKT1_HUMAN (397-605): 8.1e-17: 86.7: 10.70