Interactor 1: SIS2 (P36024)
Phosphopantothenoylcysteine decarboxylase subunit SIS2 (Halotolerance protein HAL3) (Sit4 suppressor 2)
Gene: SIS2
Interactor 2: VHS3 (Q08438)
Phosphopantothenoylcysteine decarboxylase subunit VHS3 (Viable in a HAL3 SIT4 background protein 3)
Gene: VHS3
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.68 | 1.00 | 0.829 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26514574, 37968396, unassigned1933 |
| Identification Methods | pull down, affinity chromatography technology, dihydrofolate reductase reconstruction |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Flavoprotein~Flavoprotein |
| Common GO terms | GO:0003824 - catalytic activity GO:0010181 - FMN binding GO:0015937 - coenzyme A biosynthetic process GO:0071513 - phosphopantothenoylcysteine decarboxylase complex GO:1990143 - CoA-synthesizing protein complex |
| Homologous interactions | 12 |
Homologous interactions
Color coding for hit scores 
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| + | Sc |   |
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| + | Sc | |
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| + | Sc | |
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| + | Sc | |
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| + | At | |
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| + | Sp | |
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| + | Ce | |
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| + | Hs | |
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| + | Dm | |
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| + | Ec |  |
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
