Protein: SIS2
Phosphopantothenoylcysteine decarboxylase subunit SIS2 (Halotolerance protein HAL3) (Sit4 suppressor 2)

Gene: SIS2
Organism: Saccharomyces cerevisiae S288C
Interactions: 28
UniProt ID: P36024

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0003824 - catalytic activity
GO:0004865 - protein serine/threonine phosphatase inhibitor activity
GO:0005634 - nucleus
GO:0007346 - regulation of mitotic cell cycle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

779827

CAB3
Coenzyme A biosynthesis protein 3

8

12

Small-scale

0.972

High

779826

SIS2
Phosphopantothenoylcysteine decarboxylase subunit SIS2

5

12

Small-scale

0.918

High

779838

VHS3
Phosphopantothenoylcysteine decarboxylase subunit VHS3

3

12

Small-scale

0.829

High

687045

PPZ1
Serine/threonine-protein phosphatase PP-Z1

14

7

Small-scale

0.762

High

751610

PPZ2
Serine/threonine-protein phosphatase PP-Z2

3

7

High-throughput

0.669

High

622925

CSK22
Casein kinase II subunit alpha'

3

4

High-throughput

0.647

High

481583

HSP73
Heat shock protein SSA3

2

3

High-throughput

0.588

High

721838

XPO1
Exportin-1

1

2

High-throughput

0.536

High

779829

RDH54
DNA repair and recombination protein RDH54

1

1

High-throughput

0.515

High

779837

SWR1
Helicase SWR1

1

1

High-throughput

0.515

High

437910

KAPC
cAMP-dependent protein kinase type 3

1

1

High-throughput

0.501

High

439515

PIS
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

1

High-throughput

0.494

High

528573

CP51
Lanosterol 14-alpha demethylase CYP51

1

2

High-throughput

0.494

High

779833

OSTD
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1

1

1

High-throughput

0.494

High

706764

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

779830

SSB2
Ribosome-associated molecular chaperone SSB2

1

5

High-throughput

0.479

High

544439

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.445

High

779839

RTN2
Reticulon-like protein 2

1

0

High-throughput

0.438

High

779828

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

1

High-throughput

0.437

High

609268

CPT1
Cholinephosphotransferase 1

1

1

High-throughput

0.417

High

779831

UBC7
Ubiquitin-conjugating enzyme E2 7

1

2

High-throughput

0.417

High

747676

MNS1
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

1

0

High-throughput

0.269

Low

754380

TRM2
tRNA

1

0

High-throughput

0.269

Low

779835

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

0

High-throughput

0.261

Low

779832

OSH6
Oxysterol-binding protein homolog 6

1

0

High-throughput

0.238

Low

779834

YDC1
Alkaline ceramidase YDC1

1

0

High-throughput

0.238

Low

779836

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025