Interactor 1: BCL6 (P41182)
B-cell lymphoma 6 protein (BCL-6) (B-cell lymphoma 5 protein) (BCL-5) (Protein LAZ-3) (Zinc finger and BTB domain-containing protein 27) (Zinc finger protein 51)
Gene: BCL6

Interactor 2: BCL6 (P41182)
B-cell lymphoma 6 protein (BCL-6) (B-cell lymphoma 5 protein) (BCL-5) (Protein LAZ-3) (Zinc finger and BTB domain-containing protein 27) (Zinc finger protein 51)
Gene: BCL6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.957

The method score is based on:

Property Details
Experiments 25416956, 20385364, 32296183, 19052359, 18675787, 19965633, unassigned1304
Identification Methods two hybrid, x-ray crystallography, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BTB~BTB, zf-C2H2~zf-C2H2
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000902 - cell morphogenesis
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001161 - intronic transcription regulatory region sequence-specific DNA binding
GO:0001222 - transcription corepressor binding
and 58 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 706
Hs

1 706
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Last updated: 15 Jul 2024