HitPredict

Interactor 1: KDM5C (P41229)
Lysine-specific demethylase 5C (EC 1.14.11.67) (Histone demethylase JARID1C) (Jumonji/ARID domain-containing protein 1C) (Protein SmcX) (Protein Xe169) ([histone H3]-trimethyl-L-lysine(4) demethylase 5C)
Gene: KDM5C

Interactor 2: LHX6 (Q9UPM6)
LIM/homeobox protein Lhx6 (LIM homeobox protein 6) (LIM/homeobox protein Lhx6.1)
Gene: LHX6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1560 Hs			1 363
+	Ce
		589695 KDM5_CAEEL (8-1401): 0: 972: 26.33		LIN11_CAEEL (16-349): 1.07e-53: 183: 21.27
+	Ce
		447559 KDM5_CAEEL (8-1401): 0: 972: 26.33		MEC3_CAEEL (51-296): 2.6e-44: 156: 24.04
+	Ce
		590590 KDM5_CAEEL (8-1401): 0: 972: 26.33		HM14_CAEEL (4-132): 7.57e-17: 82.7: 15.56
+	Hs
		183082 KDM6A_HUMAN (172-768): 1.23e-100: 356: 12.76		LHX1_HUMAN (70-362): 1.71e-52: 180: 26.65
+	Hs
		183085 KDM6A_HUMAN (172-768): 1.23e-100: 356: 12.76		LHX2_HUMAN (27-199): 1.4e-47: 167: 34.46
+	Hs
		183145 KDM6A_HUMAN (172-768): 1.23e-100: 356: 12.76		LHX4_HUMAN (3-124): 3.11e-19: 90: 11.81
+	Hs
		183171 KDM6A_HUMAN (172-768): 1.23e-100: 356: 12.76		LHX3_HUMAN (4-124): 2.09e-18: 87.7: 14.52