HitPredict

Interactor 1: P2RY2 (P41231)
P2Y purinoceptor 2 (P2Y2) (ATP receptor) (P2U purinoceptor 1) (P2U1) (P2U receptor 1) (Purinergic receptor)
Gene: P2RY2

Interactor 2: AT133 (Q9H7F0)
Polyamine-transporting ATPase 13A3 (ATPase family homolog up-regulated in senescence cells 1) (Putrescine transporting ATPase) (EC 7.6.2.16)
Gene: ATP13A3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 377 Hs			1 1226
+	Hs
		849708 CCR6_HUMAN (16-317): 1.12e-88: 273: 24.27		AT133_HUMAN (1-1226): 0: 1057: 100.00
+	Hs
		895742 CXCR4_HUMAN (7-329): 3.26e-75: 238: 23.85		AT132_HUMAN (21-1204): 0: 847: 40.27
+	Hs
		530845 P2RY2_HUMAN (1-377): 2.25e-82: 257: 100.00		AT1A3_HUMAN (151-1172): 0: 680: 17.78
+	Hs
		392982 ADRB2_HUMAN (2-370): 2.36e-74: 238: 13.35		AT1A1_HUMAN (151-1172): 0: 690: 18.99
+	Hs
		530862 CXCR4_HUMAN (7-329): 3.26e-75: 238: 23.85		AT1A3_HUMAN (151-1172): 0: 680: 17.78
+	Hs
		530883 GPR17_HUMAN (15-344): 1.13e-73: 235: 30.33		AT1A3_HUMAN (151-1172): 0: 680: 17.78
+	Hs
		849710 CCR6_HUMAN (16-317): 1.12e-88: 273: 24.27		AT131_HUMAN (26-1175): 0: 623: 22.23
+	Hs
		849659 CCR6_HUMAN (16-317): 1.12e-88: 273: 24.27		AT12A_HUMAN (112-1174): 0: 611: 17.28
+	Hs
		849697 CCR6_HUMAN (16-317): 1.12e-88: 273: 24.27		AT2A3_HUMAN (164-1164): 0: 596: 17.38
+	Hs
		619214 CCR6_HUMAN (16-317): 1.12e-88: 273: 24.27		AT2B4_HUMAN (140-1129): 0: 595: 16.05
+	Hs
		782415 P2RY2_HUMAN (1-377): 2.25e-82: 257: 100.00		AT12A_HUMAN (112-1174): 0: 611: 17.28
+	Hs
		782452 P2RY2_HUMAN (1-377): 2.25e-82: 257: 100.00		AT2A3_HUMAN (164-1164): 0: 596: 17.38
+	Hs
		619207 P2RY2_HUMAN (1-377): 2.25e-82: 257: 100.00		AT2B4_HUMAN (140-1129): 0: 595: 16.05
+	Hs
		782425 P2RY2_HUMAN (1-377): 2.25e-82: 257: 100.00		AT2B3_HUMAN (168-1129): 0: 595: 15.87
+	Hs
		871900 GPR17_HUMAN (15-344): 1.13e-73: 235: 30.33		AT12A_HUMAN (112-1174): 0: 611: 17.28
+	Hs
		428921 ADRB2_HUMAN (2-370): 2.36e-74: 238: 13.35		AT2B4_HUMAN (140-1129): 0: 595: 16.05
+	Hs
		895636 CXCR4_HUMAN (7-329): 3.26e-75: 238: 23.85		AT2B3_HUMAN (168-1129): 0: 595: 15.87
+	Hs
		619229 GPR17_HUMAN (15-344): 1.13e-73: 235: 30.33		AT2B4_HUMAN (140-1129): 0: 595: 16.05
+	Hs
		428908 ADRB2_HUMAN (2-370): 2.36e-74: 238: 13.35		AT2A2_HUMAN (279-1012): 1.69e-21: 103: 23.39
+	Hs
		561566 GPR17_HUMAN (15-344): 1.13e-73: 235: 30.33		AT2A2_HUMAN (279-1012): 1.69e-21: 103: 23.39