Protein: RTK1
Probable serine/threonine-protein kinase RTK1 (EC 2.7.11.1) (Ribosome biogenesis and tRNA synthetase-associated kinase 1)

Gene: RTK1
Organism: Saccharomyces cerevisiae S288C
Interactions: 84
UniProt ID: Q12100

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005935 - cellular bud neck
GO:0071944 - cell periphery
GO:0106310 - protein serine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

393499

HSP82
ATP-dependent molecular chaperone HSP82

2

15

High-throughput

0.754

High

580227

HSC82
ATP-dependent molecular chaperone HSC82

2

15

High-throughput

0.737

High

364802

CDK1
Cyclin-dependent kinase 1

1

19

High-throughput

0.724

High

623033

CSK22
Casein kinase II subunit alpha'

1

19

High-throughput

0.691

High

1026856

CDC14
Tyrosine-protein phosphatase CDC14

1

15

High-throughput

0.691

High

441291

KAPA
cAMP-dependent protein kinase type 1

1

6

High-throughput

0.647

High

448822

SNF1
Carbon catabolite-derepressing protein kinase

1

19

High-throughput

0.647

High

656667

KC11
Casein kinase I homolog 1

1

20

High-throughput

0.647

High

801952

KSP1
Serine/threonine-protein kinase KSP1

1

20

High-throughput

0.647

High

917207

ATG1
Serine/threonine-protein kinase ATG1

1

19

High-throughput

0.647

High

1030267

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

18

High-throughput

0.647

High

1043547

SKY1
Serine/threonine-protein kinase SKY1

1

19

High-throughput

0.647

High

737968

HOG1
Mitogen-activated protein kinase HOG1

1

18

Small-scale

0.621

High

815852

BEM2
GTPase-activating protein BEM2/IPL2

1

6

High-throughput

0.618

High

924350

NOP13
Nucleolar protein 13

1

4

High-throughput

0.618

High

1062350

NOP12
Nucleolar protein 12

1

7

High-throughput

0.618

High

1084301

RTK1
Probable serine/threonine-protein kinase RTK1

1

18

High-throughput

0.618

High

510898

HSP77
Import motor subunit, mitochondrial

2

15

High-throughput

0.571

High

741172

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

4

High-throughput

0.553

High

1044167

GIS1
Transcriptional activator/repressor GIS1

1

2

High-throughput

0.553

High

820078

SSB2
Ribosome-associated molecular chaperone SSB2

2

14

High-throughput

0.552

High

1065632

CUB1

2

1

High-throughput

0.548

High

858146

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

3

High-throughput

0.536

High

1043312

HAS1
ATP-dependent RNA helicase HAS1

1

7

High-throughput

0.536

High

598934

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

8

High-throughput

0.501

High

599091

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

8

High-throughput

0.501

High

625930

HNM1
Choline transporter

1

3

High-throughput

0.501

High

632760

DBP4
ATP-dependent RNA helicase HCA4

1

6

High-throughput

0.501

High

721428

MCM4
DNA replication licensing factor MCM4

1

13

High-throughput

0.501

High

830251

ARF3
ADP-ribosylation factor 3

1

3

High-throughput

0.501

High

454018

IF4E
Eukaryotic translation initiation factor 4E

1

3

High-throughput

0.489

High

722345

XPO1
Exportin-1

1

6

High-throughput

0.489

High

782485

RPF2
Ribosome biogenesis protein RPF2

1

2

High-throughput

0.489

High

858299

ARC1
tRNA-aminoacylation cofactor ARC1

1

2

High-throughput

0.489

High

919040

PESC
Pescadillo homolog

1

1

High-throughput

0.489

High

1039658

NOG1
Nucleolar GTP-binding protein 1

1

4

High-throughput

0.489

High

1047304

ERB1
Ribosome biogenesis protein ERB1

1

5

High-throughput

0.489

High

1060749

NOC3
Nucleolar complex-associated protein 3

1

1

High-throughput

0.489

High

1064859

RRS1
Regulator of ribosome biosynthesis

1

1

High-throughput

0.489

High

1084125

YTM1
Ribosome biogenesis protein YTM1

1

8

High-throughput

0.489

High

416577

HXKB
Hexokinase-2

1

1

High-throughput

0.479

High

680147

CDC48
Cell division control protein 48

1

6

High-throughput

0.479

High

807650

MLH1
DNA mismatch repair protein MLH1

1

1

High-throughput

0.479

High

816220

SPF1
Endoplasmic reticulum transmembrane helix translocase

1

3

Small-scale

0.479

High

1084257

MLH3
DNA mismatch repair protein MLH3

1

1

High-throughput

0.479

High

1084302

RIO1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.479

High

382407

H4
Histone H4

1

2

Small-scale

0.457

High

513590

RL1A
Large ribosomal subunit protein uL1A

1

3

High-throughput

0.457

High

844701

SET4
SET domain-containing protein 4

1

1

High-throughput

0.457

High

1046450

YM54
Uncharacterized protein YMR196W

1

1

High-throughput

0.457

High

368771

PMG1
Phosphoglycerate mutase 1

1

1

High-throughput

0.457

High

481806

HSP73
Heat shock protein SSA3

1

17

High-throughput

0.445

High

525485

HSP71
Heat shock protein SSA1

1

17

High-throughput

0.445

High

527969

HSP72
Heat shock protein SSA2

1

17

High-throughput

0.445

High

546676

SSB1
Ribosome-associated molecular chaperone SSB1

1

14

High-throughput

0.445

High

727388

HS104
Heat shock protein 104

1

6

High-throughput

0.445

High

816467

HSP7E
Heat shock protein SSC3, mitochondrial

1

15

High-throughput

0.445

High

594627

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.437

High

602087

SAC7
GTPase-activating protein SAC7

1

4

High-throughput

0.437

High

708488

TF2B
Transcription initiation factor IIB

1

9

High-throughput

0.437

High

748091

SMY2
Protein SMY2

1

2

High-throughput

0.437

High

807855

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

1

Small-scale

0.437

High

812753

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

864278

ALY2
Arrestin-related trafficking adapter 3

1

6

High-throughput

0.437

High

918569

ART5
Arrestin-related trafficking adapter 5

1

3

High-throughput

0.437

High

1044054

YD239
Uncharacterized protein YDR239C

1

1

High-throughput

0.437

High

1044832

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.437

High

1059407

VAM6
Vacuolar morphogenesis protein 6

1

2

High-throughput

0.437

High

1084304

SMT3
Ubiquitin-like protein SMT3

1

6

High-throughput

0.437

High

1084305

RPN6
26S proteasome regulatory subunit RPN6

1

1

High-throughput

0.437

High

919275

YG3A
Uncharacterized protein YGR130C

1

14

High-throughput

0.417

High

803502

TDA3
Putative oxidoreductase TDA3

2

0

High-throughput

0.318

High

813780

AIM2
Protein AIM2

1

0

High-throughput

0.279

Low

864345

NET1
Nucleolar protein NET1

1

0

High-throughput

0.279

Low

918238

YG1A
Uncharacterized membrane protein YGR016W

1

0

High-throughput

0.279

Low

918854

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.279

Low

757826

YBF5
Deoxyribonuclease Tat-D

1

0

High-throughput

0.261

Low

866185

EFM3
Protein-lysine N-methyltransferase EFM3

1

0

High-throughput

0.261

Low

874324

YD183
Uncharacterized protein YDL183C

1

0

High-throughput

0.261

Low

1044293

YD132
Uncharacterized protein YDR132C

1

0

High-throughput

0.261

Low

1047510

GSF2
Glucose-signaling factor 2

1

0

High-throughput

0.261

Low

1064415

MPC54
Meiotic plaque component protein 54

1

0

High-throughput

0.261

Low

1084303

HER1
HMG2-induced ER-remodeling protein 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025