HitPredict

Interactor 1: HNF4A (P41235)
Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Nuclear receptor subfamily 2 group A member 1) (Transcription factor 14) (TCF-14) (Transcription factor HNF-4)
Gene: HNF4A

Interactor 2: MED23 (Q9ULK4)
Mediator of RNA polymerase II transcription subunit 23 (Activator-recruited cofactor 130 kDa component) (ARC130) (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23) (Protein sur-2 homolog) (hSur-2) (Transcriptional coactivator CRSP130) (Vitamin D3 receptor-interacting protein complex 130 kDa component) (DRIP130)
Gene: MED23

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12089346
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 474 Hs			1 1368
+	Hs
		370690 ESR1_HUMAN (10-432): 3.46e-112: 345: 21.37		MED23_HUMAN (1-1368): 0: 2164: 100.00
+	Hs
		1269910 ESR2_HUMAN (44-374): 2.23e-99: 310: 27.64		MED23_HUMAN (1-1368): 0: 2164: 100.00
+	Mm
		1142670 ERR2_MOUSE (9-375): 1.5e-99: 307: 27.37		MED23_MOUSE (1-1368): 0: 2083: 96.27
+	Dm
		589678 USP_DROME (49-348): 8.94e-45: 165: 30.24		MED23_DROME (1-1336): 0: 1744: 48.34