Protein: 2AAA
Protein phosphatase PP2A regulatory subunit A (Protein phosphatase 2A 65 kDa regulatory subunit) (PR65)

Gene: 2AAA, paa1
Organism: Schizosaccharomyces pombe 972h-
Interactions: 147
UniProt ID: Q9UT08

Gene Ontology (top 5):
GO:0000159 - protein phosphatase type 2A complex
GO:0000775 - chromosome, centromeric region
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

661356

PP2A1
Minor serine/threonine-protein phosphatase PP2A-1 catalytic subunit

3

20

Small-scale

0.827

High

661366

PP2A2
Major serine/threonine-protein phosphatase PP2A-2 catalytic subunit

3

20

Small-scale

0.827

High

268026

RPN2
26S proteasome regulatory subunit rpn2

2

2

Small-scale

0.754

High

836499

GAR2
Protein gar2

2

7

Small-scale

0.754

High

1455066

PTPA2
Serine/threonine-protein phosphatase 2A activator 2

3

3

Small-scale

0.640

High

206914

RPN3
Probable 26S proteasome regulatory subunit rpn3

1

2

High-throughput

0.618

High

237977

IMB4
Probable importin subunit beta-4

1

4

High-throughput

0.618

High

267752

IMB3
Importin subunit beta-3

1

4

High-throughput

0.618

High

313565

G3BP
Putative G3BP-like protein

1

5

Small-scale

0.618

High

314432

YGD1
Uncharacterized WD repeat-containing protein C1773.01

1

20

High-throughput

0.618

High

1008954

2AD2
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta 2 isoform

1

20

High-throughput

0.618

High

1462910

2AAA
Protein phosphatase PP2A regulatory subunit A

1

4

Small-scale

0.618

High

785569

ALF
Fructose-bisphosphate aldolase

3

0

Small-scale

0.613

High

150452

MRD1
Multiple RNA-binding domain-containing protein 1

1

0

Small-scale

0.586

High

1018108

VIPI
Protein vip1

1

0

High-throughput

0.586

High

267559

YNVD
Uncharacterized protein C3H7.13

1

4

High-throughput

0.561

High

314296

EIF3E
Eukaryotic translation initiation factor 3 subunit E

2

0

Small-scale

0.559

High

358441

ADH
Alcohol dehydrogenase

2

0

Small-scale

0.559

High

772236

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

0

Small-scale

0.559

High

1009071

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

2

0

Small-scale

0.559

High

1068639

SDS23
Protein sds23/moc1

1

1

Small-scale

0.552

High

1082609

PDI1
Putative protein disulfide-isomerase C1F5.02

2

1

Small-scale

0.533

High

149382

PMT3
Ubiquitin-like protein pmt3/smt3

1

3

High-throughput

0.479

High

149427

DED1
ATP-dependent RNA helicase ded1

1

3

Small-scale

0.479

High

150691

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

150701

FAR11
Factor arrest protein 11

1

4

High-throughput

0.479

High

151950

ACL2
Probable ATP-citrate synthase subunit 2

1

3

High-throughput

0.479

High

152594

SYSC
Serine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

152711

YEAA
Putative 2-hydroxyacid dehydrogenase UNK4.10

1

1

High-throughput

0.479

High

152794

ZDS1
Protein zds1

1

5

High-throughput

0.479

High

152930

PRS6A
26S proteasome regulatory subunit 6A

1

5

High-throughput

0.479

High

153570

NOG2
Nucleolar GTP-binding protein 2

1

1

Small-scale

0.479

High

154003

HSP16
Heat shock protein 16

1

1

High-throughput

0.479

High

206734

FFT3
ATP-dependent helicase fft3

1

3

High-throughput

0.479

High

207178

FES1
Hsp70 nucleotide exchange factor fes1

1

4

High-throughput

0.479

High

207211

NOP14
Probable nucleolar complex protein 14

1

1

Small-scale

0.479

High

237848

HSP7F
Heat shock protein homolog pss1

1

6

High-throughput

0.479

High

237865

HSP72
Probable heat shock protein ssa2

1

7

Small-scale

0.479

High

237882

FIMB
Fimbrin

1

1

High-throughput

0.479

High

267626

SRP68
Signal recognition particle subunit srp68

1

1

High-throughput

0.479

High

268008

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

4

Small-scale

0.479

High

268432

TPX1
Peroxiredoxin tpx1

1

4

High-throughput

0.479

High

268844

SYV
Valine--tRNA ligase

1

2

Small-scale

0.479

High

314303

NOP56
Nucleolar protein 56

1

3

Small-scale

0.479

High

314766

RFC5
Replication factor C subunit 5

1

1

Small-scale

0.479

High

489142

H31
Histone H3.1/H3.2

1

3

High-throughput

0.479

High

547741

YPT1
GTP-binding protein ypt1

1

3

High-throughput

0.479

High

705038

SODC
Superoxide dismutase [Cu-Zn]

1

1

Small-scale

0.479

High

785604

YPT5
GTP-binding protein ypt5

1

4

High-throughput

0.479

High

868862

IF4A
ATP-dependent RNA helicase eIF4A

1

3

High-throughput

0.479

High

1018043

YDMC
Heat shock protein 70 homolog C57A7.12

1

9

Small-scale

0.479

High

1066607

HBA1
Brefeldin A resistance protein

1

5

High-throughput

0.479

High

1066841

PP2C3
Protein phosphatase 2C homolog 3

1

1

High-throughput

0.479

High

1068517

DBP5
ATP-dependent RNA helicase dbp5

1

5

High-throughput

0.479

High

1068682

MET10
Probable sulfite reductase [NADPH] flavoprotein component

1

1

Small-scale

0.479

High

1082764

CLH
Probable clathrin heavy chain

1

1

High-throughput

0.479

High

1082892

SSB1
Ribosome-associated molecular chaperone sks2

1

8

Small-scale

0.479

High

1082962

RPN7
26S proteasome regulatory subunit rpn7

1

1

High-throughput

0.479

High

1403846

COPA
Putative coatomer subunit alpha

1

2

High-throughput

0.479

High

1454959

RSSA2
Small ribosomal subunit protein uS2B

1

5

Small-scale

0.479

High

1455032

PPME1
Protein phosphatase methylesterase 1

1

1

High-throughput

0.479

High

1455056

FLP1
Tyrosine-protein phosphatase CDC14 homolog

1

11

Small-scale

0.479

High

1455128

RPN6
Probable 26S proteasome regulatory subunit rpn6

1

1

High-throughput

0.479

High

1455132

NOP58
Nucleolar protein 58

1

3

Small-scale

0.479

High

1455146

ACL1
Probable ATP-citrate synthase subunit 1

1

1

High-throughput

0.479

High

1462804

ERG10
Acetyl-CoA acetyltransferase

1

1

High-throughput

0.479

High

1462840

STI1
Heat shock protein sti1 homolog

1

7

High-throughput

0.479

High

1462893

APE1
Aminopeptidase 1

1

1

High-throughput

0.479

High

1462914

ALM1
Nucleoporin alm1

1

3

High-throughput

0.479

High

1462916

RSSA1
Small ribosomal subunit protein uS2A

1

5

Small-scale

0.479

High

1462918

SND1
Staphylococcal nuclease domain-containing protein 1

1

1

High-throughput

0.479

High

151800

TRP
Tryptophan synthase

1

0

High-throughput

0.458

High

151962

SYA
Alanine--tRNA ligase

1

0

High-throughput

0.458

High

152470

OLA1
Obg-like ATPase 1

1

0

High-throughput

0.458

High

152490

CBF5
H/ACA ribonucleoprotein complex subunit cbf5

1

0

Small-scale

0.458

High

152657

YEYA
Uncharacterized protein C2C4.10c

1

0

High-throughput

0.458

High

153532

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

High-throughput

0.458

High

153764

YF14
Uncharacterized protein C9E9.04

1

0

High-throughput

0.458

High

153770

YF19
Putative aldehyde dehydrogenase-like protein C9E9.09c

1

0

High-throughput

0.458

High

206037

TAL1
Transaldolase

1

0

High-throughput

0.458

High

238253

YHC3
ENTH domain-containing protein C19F8.03c

1

0

Small-scale

0.458

High

238305

METK
S-adenosylmethionine synthase

1

0

Small-scale

0.458

High

267331

RS25B
Small ribosomal subunit protein eS25B

1

0

High-throughput

0.458

High

267335

EF1B
Elongation factor 1-beta

1

0

High-throughput

0.458

High

268295

ESF1
Pre-rRNA-processing protein esf1

1

0

Small-scale

0.458

High

268296

YC12
Putative glutathione S-transferase C1183.02

1

0

High-throughput

0.458

High

314117

MUG35
Meiotically up-regulated gene 35 protein

1

0

High-throughput

0.458

High

314577

JHD1
Putative JmjC domain-containing histone demethylation protein 1

1

0

High-throughput

0.458

High

314815

YCFC
Uncharacterized protein C1393.12

1

0

High-throughput

0.458

High

458894

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

613662

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.458

High

639886

GPD1
Glycerol-3-phosphate dehydrogenase [NAD(+)] 1

1

0

High-throughput

0.458

High

785771

CAP
Adenylyl cyclase-associated protein

1

0

High-throughput

0.458

High

869430

H2AZ
Histone H2A.Z

1

0

Small-scale

0.458

High

947847

RL37A
Large ribosomal subunit protein eL37A

1

0

High-throughput

0.458

High

1008978

UGPA1
Probable UTP--glucose-1-phosphate uridylyltransferase

1

0

Small-scale

0.458

High

1008980

6PGD
6-phosphogluconate dehydrogenase, decarboxylating

1

0

High-throughput

0.458

High

1068522

DNM1
Dynamin-related protein dnm1

1

0

High-throughput

0.458

High

1068528

HXK1
Hexokinase-1

1

0

High-throughput

0.458

High

1082640

UTP11
Probable U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

1082701

YAS4
Uncharacterized protein C3H8.04

1

0

High-throughput

0.458

High

1082842

KPYK
Pyruvate kinase

1

0

Small-scale

0.458

High

1082869

CMB1
Cytosine-containing mismatch-binding protein 1

1

0

High-throughput

0.458

High

1082875

MUG64
Meiotically up-regulated gene 64 protein

1

0

High-throughput

0.458

High

1082969

TCTP
Translationally-controlled tumor protein homolog

1

0

High-throughput

0.458

High

1082974

SERC
Putative phosphoserine aminotransferase

1

0

High-throughput

0.458

High

1083023

SPO15
Sporulation-specific protein 15

1

0

High-throughput

0.458

High

1083485

SPD1
S-phase delaying protein 1

1

0

Small-scale

0.458

High

1439770

YK18
Meiotically up-regulated protein PB1A10.08

1

0

High-throughput

0.458

High

1454964

CUB1
CUB1 family protein C30C2.08

1

0

High-throughput

0.458

High

1455018

SGO1
Shugoshin-1

1

0

Small-scale

0.458

High

1455107

OAT
Ornithine aminotransferase car2

1

0

High-throughput

0.458

High

1455116

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

0

High-throughput

0.458

High

1462825

BFR2
Protein bfr2

1

0

Small-scale

0.458

High

1462828

RPN9
Probable 26S proteasome regulatory subunit rpn9

1

0

High-throughput

0.458

High

1462873

IF5A2
Eukaryotic translation initiation factor 5A-2

1

0

High-throughput

0.458

High

1462911

METE
Probable 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

0

High-throughput

0.458

High

1462912

SEY1
Protein sey1

1

0

High-throughput

0.458

High

1462913

PLB2
Probable lysophospholipase 2

1

0

High-throughput

0.458

High

1462915

TPSY
Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 100 kDa subunit

1

0

High-throughput

0.458

High

1462917

MUG72
Meiotically up-regulated gene 72 protein

1

0

Small-scale

0.458

High

151726

PDI2
Protein disulfide-isomerase C17H9.14c

1

1

High-throughput

0.437

High

152709

ATC4
Endoplasmic reticulum transmembrane helix translocase

1

2

High-throughput

0.437

High

237558

SPTC1
Serine palmitoyltransferase 1

1

1

High-throughput

0.437

High

237878

OSTB
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit wbp1

1

1

High-throughput

0.437

High

314364

PHB2
Prohibitin-2

1

6

High-throughput

0.437

High

534542

ACT
Actin

1

1

Small-scale

0.437

High

785575

CALX
Calnexin homolog

1

1

High-throughput

0.437

High

1008996

GHT5
High-affinity glucose transporter ght5

1

1

High-throughput

0.437

High

1068659

HSP60
Heat shock protein 60, mitochondrial

1

2

Small-scale

0.437

High

1068743

LCB2
Serine palmitoyltransferase 2

1

1

High-throughput

0.437

High

1082790

OST1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.437

High

1082829

DBP3
ATP-dependent RNA helicase dbp3

1

1

Small-scale

0.437

High

151924

PMT1
Dolichyl-phosphate-mannose--protein mannosyltransferase 1

1

0

High-throughput

0.249

Low

152072

ECM33
Cell wall protein ecm33

1

0

High-throughput

0.249

Low

207207

ERG26
Sterol-4-alpha-carboxylate 3-dehydrogenase erg26, decarboxylating

1

0

High-throughput

0.249

Low

238034

PPB
Alkaline phosphatase

1

0

Small-scale

0.249

Low

267784

DUC1
DUF1769 family protein duc1

1

0

Small-scale

0.249

Low

313551

LCMT1
Leucine carboxyl methyltransferase 1

1

0

Small-scale

0.249

Low

1018088

BUT2
Uba3-binding protein but2

1

0

High-throughput

0.249

Low

1066840

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.249

Low

1066856

ADT
ADP,ATP carrier protein

1

0

Small-scale

0.249

Low

1083226

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

1455043

YKY4
Uncharacterized NOC2 family protein C1142.04

1

0

High-throughput

0.249

Low

1462909

YKH3
Uncharacterized protein PYUK71.03c

1

0

High-throughput

0.249

Low

1462919

ISH1
Stress response protein ish1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025