HitPredict

Interactor 1: SYIC (P41252)
Isoleucine--tRNA ligase, cytoplasmic (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IRS) (IleRS)
Gene: IARS1

Interactor 2: WDR76 (Q9H967)
WD repeat-containing protein 76
Gene: WDR76

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	27248496
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1262 Hs			1 626
+	Hs
		783074 SYIC_HUMAN (1-1262): 0: 1480: 100.00		COP1_HUMAN (154-619): 7.6e-71: 245: 14.96
+	Hs
		783084 SYIC_HUMAN (1-1262): 0: 1480: 100.00		FBXW7_HUMAN (180-616): 3.15e-66: 231: 11.79
+	Hs
		782977 SYIC_HUMAN (1-1262): 0: 1480: 100.00		LIS1_HUMAN (118-478): 6.33e-51: 183: 9.73
+	Hs
		783000 SYIC_HUMAN (1-1262): 0: 1480: 100.00		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		643912 SYVC_HUMAN (1-961): 0: 823: 19.24		WDR76_HUMAN (1-626): 1.19e-151: 453: 100.00
+	Sc
		450350 SYIC_YEAST (2-1071): 0: 1020: 52.93		CMR1_YEAST (159-623): 1.38e-74: 249: 23.50
+	Hs
		1334038 SYLC_HUMAN (3-993): 0: 668: 16.08		WDR76_HUMAN (1-626): 1.19e-151: 453: 100.00
+	Ce
		953991 SYIC_CAEEL (2-1077): 0: 1019: 57.96		LIN53_CAEEL (251-477): 2.75e-20: 95.7: 15.73
+	Hs
		643838 SYVC_HUMAN (1-961): 0: 823: 19.24		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		1281442 SYLC_HUMAN (3-993): 0: 668: 16.08		FBXW7_HUMAN (180-616): 3.15e-66: 231: 11.79
+	Ce
		954098 SYV_CAEEL (3-992): 0: 791: 19.66		LIN53_CAEEL (251-477): 2.75e-20: 95.7: 15.73
+	Ce
		953907 SYLC_CAEEL (1-1008): 0: 616: 15.51		LIN53_CAEEL (251-477): 2.75e-20: 95.7: 15.73