HitPredict

Interactor 1: BUB1 (P41695)
Checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1)
Gene: BUB1

Interactor 2: BUB1 (P41695)
Checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1)
Gene: BUB1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.848

The method score is based on:

Property Details
Experiments 18547097, 19141287
Identification Methods pull down, affinity chromatography technology, molecular sieving, circular dichroism, x-ray crystallography, x ray scattering, mass spectrometry studies of complexes
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Mad3_BUB1_I~Mad3_BUB1_I, Mad3_BUB1_II~Mad3_BUB1_II, Pkinase~Pkinase
Common GO terms GO:0000776 - kinetochore
GO:0000779 - condensed chromosome, centromeric region
GO:0000940 - outer kinetochore
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
and 11 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1021
Sc

1 1021
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+ Hs
+ Hs
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+ Hs
+ Rn
+ Hs
+ Sp
+ Hs
+ Rn
+ Mm
+ Hs
+ At
+ Hs
+ At
+ At
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024