Protein: RM46
Large ribosomal subunit protein mL46 (39S ribosomal protein L46, mitochondrial) (L46mt) (MRP-L46) (P2ECSL)

Gene: RM46, MRPL46
Organism: Homo sapiens
Interactions: 174
UniProt ID: Q9H2W6

Gene Ontology (top 5):
GO:0003735 - structural constituent of ribosome
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005762 - mitochondrial large ribosomal subunit

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1432236

RM40
Large ribosomal subunit protein mL40

5

1

High-throughput

0.919

High

1281129

RM55
Large ribosomal subunit protein mL55

6

0

High-throughput

0.892

High

1391608

RM48
Large ribosomal subunit protein mL48

3

1

High-throughput

0.667

High

1418237

RM04
Large ribosomal subunit protein uL4m

3

1

High-throughput

0.667

High

1432232

RM47
Large ribosomal subunit protein uL29m

3

1

High-throughput

0.667

High

1234688

ETFR1
Electron transfer flavoprotein regulatory factor 1

4

0

High-throughput

0.664

High

1328289

RM50
Large ribosomal subunit protein mL50

3

0

High-throughput

0.646

High

1410873

MGME1
Mitochondrial genome maintenance exonuclease 1

3

0

High-throughput

0.638

High

1419634

RM37
Large ribosomal subunit protein mL37

3

0

High-throughput

0.638

High

1432233

RT30
Large ribosomal subunit protein mL65

3

0

High-throughput

0.638

High

1432247

RM39
Large ribosomal subunit protein mL39

3

0

High-throughput

0.638

High

1432259

RM42
Large ribosomal subunit protein mL42

3

0

High-throughput

0.634

High

969438

RS8
Small ribosomal subunit protein eS8

2

1

High-throughput

0.611

High

1094116

RM28
Large ribosomal subunit protein bL28m

2

1

High-throughput

0.611

High

1432257

RM11
Large ribosomal subunit protein uL11m

2

1

High-throughput

0.611

High

1281335

RM10
Large ribosomal subunit protein uL10m

2

0

High-throughput

0.602

High

1312759

RM41
Large ribosomal subunit protein mL41

2

0

High-throughput

0.602

High

1418185

RM09
Large ribosomal subunit protein bL9m

2

0

High-throughput

0.602

High

914748

RM12
Large ribosomal subunit protein bL12m

2

1

High-throughput

0.601

High

156500

ACPM
Acyl carrier protein, mitochondrial

2

0

High-throughput

0.585

High

693975

RL10
Large ribosomal subunit protein uL16

2

0

High-throughput

0.585

High

1123425

ICT1
Large ribosomal subunit protein mL62

2

0

High-throughput

0.585

High

1087548

GRSF1
G-rich sequence factor 1

2

1

High-throughput

0.584

High

1430501

RM18
Large ribosomal subunit protein uL18m

2

0

High-throughput

0.576

High

279910

CISY
Citrate synthase, mitochondrial

2

0

High-throughput

0.559

High

1058271

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

2

0

Small-scale

0.559

High

1162546

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

0

High-throughput

0.559

High

1432252

MRES1
Mitochondrial transcription rescue factor 1

2

0

High-throughput

0.559

High

477861

RM03
Large ribosomal subunit protein uL3m

1

2

High-throughput

0.536

High

978722

RL23A
Large ribosomal subunit protein uL23

1

1

High-throughput

0.536

High

1148790

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

2

High-throughput

0.536

High

1213339

RM02
Large ribosomal subunit protein uL2m

1

1

High-throughput

0.536

High

1251045

RBMS3
RNA-binding motif, single-stranded-interacting protein 3

1

2

High-throughput

0.536

High

1387954

RM38
Large ribosomal subunit protein mL38

1

1

High-throughput

0.536

High

1418128

RM13
Large ribosomal subunit protein uL13m

1

1

High-throughput

0.536

High

1432230

RM44
Large ribosomal subunit protein mL44

1

1

High-throughput

0.536

High

1432239

RM17
Large ribosomal subunit protein bL17m

1

1

High-throughput

0.536

High

1432246

RM16
Large ribosomal subunit protein uL16m

1

1

High-throughput

0.536

High

1432250

RM15
Large ribosomal subunit protein uL15m

1

1

High-throughput

0.536

High

1432251

RM27
Large ribosomal subunit protein bL27m

1

1

High-throughput

0.536

High

76037

B4DEF8
Large ribosomal subunit protein mL45

1

0

High-throughput

0.513

High

144316

ACACB
Acetyl-CoA carboxylase 2

1

0

High-throughput

0.513

High

615980

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.513

High

748712

CGL
Cystathionine gamma-lyase

1

0

High-throughput

0.513

High

842534

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.513

High

867414

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

1016225

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.513

High

1027749

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

0

High-throughput

0.513

High

1104095

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.513

High

1129124

PLSI
Plastin-1

1

0

High-throughput

0.513

High

1158294

RM23
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.513

High

1196163

RM51
Large ribosomal subunit protein mL51

1

0

High-throughput

0.513

High

1242629

FAHD1
Oxaloacetate tautomerase FAHD1, mitochondrial

1

0

High-throughput

0.513

High

1287547

RM52
Large ribosomal subunit protein mL52

1

0

High-throughput

0.513

High

1347078

G45IP
Large ribosomal subunit protein mL64

1

0

High-throughput

0.513

High

1349547

RM30
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.513

High

1382295

RM24
Large ribosomal subunit protein uL24m

1

0

High-throughput

0.513

High

1389005

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

1

0

High-throughput

0.513

High

1389277

RM53
Large ribosomal subunit protein mL53

1

0

High-throughput

0.513

High

1410494

RT63
Large ribosomal subunit protein mL63

1

0

High-throughput

0.513

High

1418063

RM32
Large ribosomal subunit protein bL32m

1

0

High-throughput

0.513

High

1418093

RM20
Large ribosomal subunit protein bL20m

1

0

High-throughput

0.513

High

1432231

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.513

High

1432238

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.513

High

1432243

RT18A
Large ribosomal subunit protein mL66

1

0

High-throughput

0.513

High

1432249

RM35
Large ribosomal subunit protein bL35m

1

0

High-throughput

0.513

High

407894

SEMG1
Semenogelin-1

1

1

High-throughput

0.489

High

1036593

SEMG2
Semenogelin-2

1

1

High-throughput

0.489

High

282083

MPPB
Mitochondrial-processing peptidase subunit beta

1

1

High-throughput

0.479

High

287379

RF1M
Peptide chain release factor 1, mitochondrial

1

2

High-throughput

0.479

High

350995

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

1

High-throughput

0.479

High

373130

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

406634

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

473078

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

2

High-throughput

0.479

High

532961

CH60
60 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.479

High

856382

IF2M
Translation initiation factor IF-2, mitochondrial

1

2

High-throughput

0.479

High

1083746

MPPA
Mitochondrial-processing peptidase subunit alpha

1

1

High-throughput

0.479

High

1138625

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

1194373

LARP7
La-related protein 7

1

1

High-throughput

0.479

High

1207443

HABP4
Intracellular hyaluronan-binding protein 4

1

1

High-throughput

0.479

High

1334904

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

1340667

NEDD1
Protein NEDD1

1

1

High-throughput

0.479

High

1381122

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

2

High-throughput

0.479

High

1381721

FAKD4
FAST kinase domain-containing protein 4

1

1

High-throughput

0.479

High

1388273

RRFM
Ribosome-recycling factor, mitochondrial

1

1

High-throughput

0.479

High

1401613

EFGM
Elongation factor G, mitochondrial

1

2

High-throughput

0.479

High

1412431

TACO1
Translational activator of cytochrome c oxidase 1

1

1

High-throughput

0.479

High

1428725

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

1

High-throughput

0.479

High

1432226

MTRFR
Mitochondrial translation release factor in rescue

1

2

High-throughput

0.479

High

1432240

DDX28
Probable ATP-dependent RNA helicase DDX28

1

1

High-throughput

0.479

High

1432248

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

1

High-throughput

0.479

High

1432253

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

2

High-throughput

0.479

High

1432256

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.479

High

1337544

MCPH1
Microcephalin

1

0

Small-scale

0.460

High

61632

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.458

High

66289

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.458

High

183736

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.458

High

242904

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

254428

CC14B
Dual specificity protein phosphatase CDC14B

1

0

High-throughput

0.458

High

275103

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

283968

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

0

High-throughput

0.458

High

316007

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

447433

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

471246

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.458

High

485413

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

High-throughput

0.458

High

519225

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

680501

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

810369

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

828955

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

841942

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

852029

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

882882

EFTU
Elongation factor Tu, mitochondrial

1

0

High-throughput

0.458

High

905136

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

965237

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.458

High

971070

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1015777

RHOG
Rho-related GTP-binding protein RhoG

1

0

High-throughput

0.458

High

1024181

TFAM
Transcription factor A, mitochondrial

1

0

High-throughput

0.458

High

1039396

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.458

High

1048693

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1051315

KPCZ
Protein kinase C zeta type

1

0

High-throughput

0.458

High

1090536

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

0

High-throughput

0.458

High

1092241

NFX1
Transcriptional repressor NF-X1

1

0

High-throughput

0.458

High

1117841

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.458

High

1142666

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

1156857

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

1161666

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1207138

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1234527

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

1241347

CH082
UPF0598 protein C8orf82

1

0

High-throughput

0.458

High

1271547

DHX30
ATP-dependent RNA helicase DHX30

1

0

High-throughput

0.458

High

1310399

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.458

High

1368615

KAT6A
Histone acetyltransferase KAT6A

1

0

High-throughput

0.458

High

1380748

RL36L
Ribosomal protein eL42-like

1

0

High-throughput

0.458

High

1386019

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

0

High-throughput

0.458

High

1387760

FMT
Methionyl-tRNA formyltransferase, mitochondrial

1

0

High-throughput

0.458

High

1388405

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.458

High

1393288

FMC1
Protein FMC1 homolog

1

0

High-throughput

0.458

High

1400817

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.458

High

1403425

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.458

High

1412581

CQ080
Mitochondrial nucleoid-associated protein 1

1

0

High-throughput

0.458

High

1413016

MTG1
Mitochondrial ribosome-associated GTPase 1

1

0

High-throughput

0.458

High

1414087

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.458

High

1414564

DDX23
Probable ATP-dependent RNA helicase DDX23

1

0

High-throughput

0.458

High

1415669

TR61B
tRNA

1

0

High-throughput

0.458

High

1416541

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.458

High

1418877

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

1428805

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

0

High-throughput

0.458

High

1431962

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.458

High

1432225

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

1432227

MTG2
Mitochondrial ribosome-associated GTPase 2

1

0

High-throughput

0.458

High

1432228

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1432229

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

1432234

NGRN
Neugrin

1

0

High-throughput

0.458

High

1432237

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

1432241

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

1432244

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

0

High-throughput

0.458

High

1432245

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

1432254

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1214787

ATD3B
ATPase family AAA domain-containing protein 3B

1

1

High-throughput

0.445

High

1227446

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.445

High

1432242

ATD3A
ATPase family AAA domain-containing protein 3A

1

1

High-throughput

0.445

High

1432258

MAFB
Transcription factor MafB

1

1

High-throughput

0.437

High

430352

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

442806

RB
Retinoblastoma-associated protein

1

0

High-throughput

0.426

High

530370

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

1132435

CASP8
Caspase-8

1

0

High-throughput

0.426

High

1403977

SCN2A
Sodium channel protein type 2 subunit alpha

1

0

High-throughput

0.279

Low

1136363

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.249

Low

1215825

RC3H1
Roquin-1

1

0

High-throughput

0.249

Low

1271856

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.249

Low

1327190

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

1393687

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1432235

LUC7L
Putative RNA-binding protein Luc7-like 1

1

0

High-throughput

0.249

Low

1432255

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025