HitPredict

Interactor 1: PRS8 (P41836)
26S proteasome regulatory subunit 8 homolog (Protein let1)
Gene: let1

Interactor 2: RPN6 (Q9P7S2)
Probable 26S proteasome regulatory subunit rpn6
Gene: RPN6

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	22187461
Identification Methods	x-ray crystallography
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 403 Sp			1 421
+	Sp
		251481 PRS10_SCHPO (21-401): 7.3e-156: 446: 45.29		RPN6_SCHPO (1-421): 3.81e-105: 319: 100.00
+	Hs
		121726 PRS4_HUMAN (9-395): 9.52e-136: 397: 45.48		PSD11_HUMAN (1-419): 5.79e-106: 321: 53.79
+	Dm
		820482 PRS4_DROME (7-395): 1.05e-135: 397: 44.22		PSD11_DROME (1-419): 1.51e-104: 317: 52.61
+	At
		1338958 PRS4A_ARATH (7-393): 5.26e-135: 395: 45.22		PSD11_ARATH (1-420): 1.93e-101: 309: 48.81
+	Hs
		897225 PRS4_HUMAN (9-395): 9.52e-136: 397: 45.48		CSN2_HUMAN (11-417): 1.15e-93: 290: 20.53
+	Hs
		121703 PRS6B_HUMAN (10-396): 9.6e-118: 350: 42.12		PSD11_HUMAN (1-419): 5.79e-106: 321: 53.79
+	Hs
		906832 PRS4_HUMAN (9-395): 9.52e-136: 397: 45.48		PSMD6_HUMAN (25-419): 2.75e-87: 272: 14.53
+	Hs
		121699 PRS7_HUMAN (80-388): 2.37e-112: 337: 56.31		PSD11_HUMAN (1-419): 5.79e-106: 321: 53.79
+	Hs
		121983 PRS4_HUMAN (9-395): 9.52e-136: 397: 45.48		PSD12_HUMAN (7-420): 2.44e-82: 261: 12.70
+	Dm
		820500 PRS4_DROME (7-395): 1.05e-135: 397: 44.22		PSMD6_DROME (27-419): 3.57e-81: 256: 13.86
+	Dm
		1180706 Q7KMQ0_DROME (80-388): 3.53e-111: 334: 55.34		PSD11_DROME (1-419): 1.51e-104: 317: 52.61
+	Sc
		968100 PRS8_YEAST (6-403): 7.89e-121: 358: 76.38		RPN6_YEAST (4-419): 3.71e-90: 281: 47.55
+	At
		1275275 PRS4A_ARATH (7-393): 5.26e-135: 395: 45.22		PSMD6_ARATH (57-411): 5.6e-70: 227: 13.41
+	Hs
		798666 PRS6B_HUMAN (10-396): 9.6e-118: 350: 42.12		PSMD6_HUMAN (25-419): 2.75e-87: 272: 14.53
+	Dm
		820499 PRS4_DROME (7-395): 1.05e-135: 397: 44.22		CSN4_DROME (50-413): 1.58e-66: 219: 15.13
+	Sc
		703976 PRS7_YEAST (80-389): 1.94e-109: 331: 55.81		RPN6_YEAST (4-419): 3.71e-90: 281: 47.55
+	Hs
		121959 PRS6B_HUMAN (10-396): 9.6e-118: 350: 42.12		PSD12_HUMAN (7-420): 2.44e-82: 261: 12.70
+	Hs
		730263 PRS7_HUMAN (80-388): 2.37e-112: 337: 56.31		PSMD6_HUMAN (25-419): 2.75e-87: 272: 14.53
+	Hs
		121953 PRS7_HUMAN (80-388): 2.37e-112: 337: 56.31		PSD12_HUMAN (7-420): 2.44e-82: 261: 12.70
+	Dm
		1180728 Q9W414_DROME (4-94): 1.61e-11: 67.5: 13.19		PSD11_DROME (1-419): 1.51e-104: 317: 52.61