HitPredict

Interactor 1: ELK3 (P41970)
ETS domain-containing protein Elk-3 (ETS-related protein ERP) (ETS-related protein NET) (Serum response factor accessory protein 2) (SAP-2) (SRF accessory protein 2)
Gene: ELK3

Interactor 2: BRD8 (Q9H0E9)
Bromodomain-containing protein 8 (Skeletal muscle abundant protein) (Skeletal muscle abundant protein 2) (Thyroid hormone receptor coactivating protein of 120 kDa) (TrCP120) (p120)
Gene: BRD8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005739 - mitochondrion GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 407 Hs			1 1235
+	Hs
		785414 ELK3_HUMAN (19-407): 1.88e-65: 216: 100.00		BRD7_HUMAN (1005-1212): 3.07e-29: 127: 15.02
+	Hs
		542009 ETS1_HUMAN (3-111): 1.03e-45: 164: 45.87		BPTF_HUMAN (130-1222): 5.45e-42: 171: 9.55
+	Hs
		1017302 ELF2_HUMAN (4-376): 1.62e-41: 156: 21.87		BPTF_HUMAN (130-1222): 5.45e-42: 171: 9.55
+	Hs
		785379 ELK3_HUMAN (19-407): 1.88e-65: 216: 100.00		PB1_HUMAN (987-1226): 1.89e-22: 107: 15.45
+	Hs
		600093 ELK3_HUMAN (19-407): 1.88e-65: 216: 100.00		TAF1_HUMAN (1002-1220): 5.29e-22: 105: 15.32
+	Hs
		542054 ETS1_HUMAN (3-111): 1.03e-45: 164: 45.87		KAT2B_HUMAN (1075-1209): 2.89e-37: 154: 23.70
+	Hs
		170240 ETS1_HUMAN (3-111): 1.03e-45: 164: 45.87		TIF1A_HUMAN (845-1228): 4.33e-31: 134: 14.07
+	Hs
		987759 GABPA_HUMAN (2-137): 6.47e-48: 171: 42.65		EP300_HUMAN (807-1211): 2.38e-27: 123: 13.66
+	Hs
		542075 ETS1_HUMAN (3-111): 1.03e-45: 164: 45.87		BRD7_HUMAN (1005-1212): 3.07e-29: 127: 15.02
+	Hs
		542006 ETS1_HUMAN (3-111): 1.03e-45: 164: 45.87		EP300_HUMAN (807-1211): 2.38e-27: 123: 13.66
+	Hs
		542741 ETS2_HUMAN (3-111): 9.5e-45: 162: 46.79		EP300_HUMAN (807-1211): 2.38e-27: 123: 13.66
+	Hs
		542036 ETS1_HUMAN (3-111): 1.03e-45: 164: 45.87		PB1_HUMAN (987-1226): 1.89e-22: 107: 15.45
+	Hs
		541993 ETS1_HUMAN (3-111): 1.03e-45: 164: 45.87		SMCA4_HUMAN (1057-1208): 7.26e-19: 95.5: 13.84
+	Mm
		101434 GABPA_MOUSE (2-133): 3.23e-47: 169: 44.70		F8VPR5_MOUSE (105-556): 1.4e-10: 68.4: 9.87
+	Mm
		649230 ETS1_MOUSE (3-110): 3.44e-45: 163: 46.30		CBP_MOUSE (105-556): 9.35e-11: 68.8: 9.87
+	Mm
		101425 ETS1_MOUSE (3-110): 3.44e-45: 163: 46.30		F8VPR5_MOUSE (105-556): 1.4e-10: 68.4: 9.87
+	Mm
		542771 ETS2_MOUSE (3-111): 9.24e-45: 162: 46.79		CBP_MOUSE (105-556): 9.35e-11: 68.8: 9.87
+	Mm
		101419 ETS2_MOUSE (3-111): 9.24e-45: 162: 46.79		F8VPR5_MOUSE (105-556): 1.4e-10: 68.4: 9.87
+	Hs
		542053 ETS1_HUMAN (3-111): 1.03e-45: 164: 45.87		CBP_HUMAN (125-595): 9.03e-09: 62.2: 12.22
+	Hs
		542756 ETS2_HUMAN (3-111): 9.5e-45: 162: 46.79		CBP_HUMAN (125-595): 9.03e-09: 62.2: 12.22