HitPredict

Interactor 1: LAP2B (P42167)
Lamina-associated polypeptide 2, isoforms beta/gamma (Thymopoietin, isoforms beta/gamma) (TP beta/gamma) (Thymopoietin-related peptide isoforms beta/gamma) (TPRP isoforms beta/gamma) [Cleaved into: Thymopoietin (TP) (Splenin); Thymopentin (TP5)]
Gene: TMPO

Interactor 2: WRN (Q14191)
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (DNA helicase, RecQ-like type 3) (RecQ protein-like 2) (Werner syndrome protein) [Includes: 3'-5' exonuclease (EC 3.1.-.-); ATP-dependent helicase (EC 5.6.2.4) (DNA 3'-5' helicase WRN)]
Gene: WRN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	25931448
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 1432
+	Hs
		785738 LAP2B_HUMAN (1-454): 0: 612: 100.00		RECQ1_HUMAN (461-1117): 3.09e-152: 478: 26.11
+	Hs
		294481 LAP2B_HUMAN (1-454): 0: 612: 100.00		RECQ4_HUMAN (530-878): 2.42e-118: 402: 29.95
+	Hs
		785981 LAP2B_HUMAN (1-454): 0: 612: 100.00		DDX46_HUMAN (278-1201): 6e-120: 402: 12.60
+	Hs
		133916 LAP2B_HUMAN (1-454): 0: 612: 100.00		DDX3X_HUMAN (354-901): 6.63e-119: 389: 14.85
+	Hs
		786059 LAP2B_HUMAN (1-454): 0: 612: 100.00		DDX17_HUMAN (469-955): 1.98e-117: 387: 16.54
+	Hs
		571340 LAP2B_HUMAN (1-454): 0: 612: 100.00		DDX5_HUMAN (469-892): 8.41e-112: 368: 16.96