HitPredict

Interactor 1: STAT1 (P42224)
Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84)
Gene: STAT1

Interactor 2: STAT4 (Q14765)
Signal transducer and activator of transcription 4
Gene: STAT4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 21826217, 33961781, 35140242
Identification Methods pull down, affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH2, STAT_alpha~STAT_bind, STAT_alpha~STAT_int, STAT_bind~STAT_bind, STAT_int~STAT_int
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
and 9 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 750
Hs

1 748
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Last updated: 15 Jul 2024