Protein: TINF2
TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2)

Gene: TINF2
Organism: Homo sapiens
Interactions: 134
UniProt ID: Q9BSI4

Gene Ontology (top 5):
GO:0000781 - chromosome, telomeric region
GO:0000783 - nuclear telomere cap complex
GO:0005654 - nucleoplasm
GO:0010370 - perinucleolar chromocenter
GO:0016233 - telomere capping

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

928536

TERF1
Telomeric repeat-binding factor 1

20

2

Small-scale

0.766

High

1383369

ACD
Adrenocortical dysplasia protein homolog

14

1

Small-scale

0.765

High

1149975

TERF2
Telomeric repeat-binding factor 2

13

2

Small-scale

0.764

High

1412513

POTE1
Protection of telomeres protein 1

11

0

Small-scale

0.728

High

1412516

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

8

0

Small-scale

0.723

High

332440

TNKS1
Poly [ADP-ribose] polymerase tankyrase-1

3

0

Small-scale

0.634

High

799446

BRCA1
Breast cancer type 1 susceptibility protein

2

1

Small-scale

0.584

High

1412517

AIPL1
Aryl-hydrocarbon-interacting protein-like 1

1

2

High-throughput

0.573

High

1412523

NUDC
Nuclear migration protein nudC

1

1

High-throughput

0.552

High

211593

SIAH2
E3 ubiquitin-protein ligase SIAH2

1

0

Small-scale

0.549

High

220450

RGS14
Regulator of G-protein signaling 14

1

0

High-throughput

0.549

High

261439

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

0

High-throughput

0.549

High

271292

CPNE3
Copine-3

1

0

High-throughput

0.549

High

347900

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.549

High

436727

KPCB
Protein kinase C beta type

1

0

High-throughput

0.549

High

476796

RSSA
Small ribosomal subunit protein uS2

1

0

High-throughput

0.549

High

489056

LKHA4
Leukotriene A-4 hydrolase

1

0

High-throughput

0.549

High

858708

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

0

High-throughput

0.549

High

889801

CLK3
Dual specificity protein kinase CLK3

1

0

High-throughput

0.549

High

953062

ACTB
Actin, cytoplasmic 1

1

0

High-throughput

0.549

High

1150889

CIP4
Cdc42-interacting protein 4

1

0

High-throughput

0.549

High

1293563

F131B
Protein FAM131B

1

0

High-throughput

0.549

High

1309366

ARI3B
AT-rich interactive domain-containing protein 3B

1

0

High-throughput

0.549

High

163586

TPP1
Tripeptidyl-peptidase 1

1

0

Small-scale

0.537

High

572170

TRI27
Zinc finger protein RFP

1

1

High-throughput

0.536

High

1106055

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

2

High-throughput

0.536

High

390744

TFR1
Transferrin receptor protein 1

1

1

Small-scale

0.535

High

123434

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

0

High-throughput

0.529

High

134136

IPO5
Importin-5

1

0

High-throughput

0.529

High

214511

HXA3
Homeobox protein Hox-A3

1

0

High-throughput

0.529

High

468746

HS90B
Heat shock protein HSP 90-beta

1

0

High-throughput

0.529

High

488543

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

0

High-throughput

0.529

High

714954

EF1D
Elongation factor 1-delta

1

0

High-throughput

0.529

High

893449

HNMT
Histamine N-methyltransferase

1

0

High-throughput

0.529

High

1204793

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

0

High-throughput

0.529

High

1412512

PHP14
14 kDa phosphohistidine phosphatase

1

0

High-throughput

0.529

High

334356

TRI16
Tripartite motif-containing protein 16

1

1

High-throughput

0.523

High

457655

TBB5
Tubulin beta chain

1

3

High-throughput

0.523

High

476189

ANXA5
Annexin A5

1

3

High-throughput

0.523

High

483458

ANXA4
Annexin A4

1

3

High-throughput

0.523

High

786350

PGM1
Phosphoglucomutase-1

1

1

High-throughput

0.523

High

1153733

TOM34
Mitochondrial import receptor subunit TOM34

1

1

High-throughput

0.523

High

1391226

PGM2
Phosphopentomutase

1

1

High-throughput

0.523

High

558371

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.513

High

1008316

PRKDC
DNA-dependent protein kinase catalytic subunit

1

0

High-throughput

0.513

High

1122953

WRN
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN

1

0

High-throughput

0.513

High

1412505

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.513

High

1412510

DCR1B
5' exonuclease Apollo

1

0

High-throughput

0.513

High

276719

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

1

2

High-throughput

0.504

High

997483

TBB4B
Tubulin beta-4B chain

1

3

High-throughput

0.504

High

1124702

SRC8
Src substrate cortactin

1

1

High-throughput

0.504

High

1133161

LASP1
LIM and SH3 domain protein 1

1

1

High-throughput

0.504

High

1358102

NUDC2
NudC domain-containing protein 2

1

1

High-throughput

0.504

High

1412506

TRI15
E3 ubiquitin-protein ligase TRIM15

1

1

High-throughput

0.504

High

1358298

STAG1
Cohesin subunit SA-1

1

0

Small-scale

0.493

High

408145

TBB4A
Tubulin beta-4A chain

1

3

High-throughput

0.489

High

1412521

CHIP
E3 ubiquitin-protein ligase CHIP

1

1

High-throughput

0.481

High

997978

CSK21
Casein kinase II subunit alpha

1

0

Small-scale

0.480

High

639811

TAF1
Transcription initiation factor TFIID subunit 1

1

1

High-throughput

0.479

High

892931

MRE11
Double-strand break repair protein MRE11

1

1

High-throughput

0.479

High

989922

CANB1
Calcineurin subunit B type 1

1

1

High-throughput

0.479

High

1088999

TP53B
TP53-binding protein 1

1

1

High-throughput

0.479

High

1129721

MDC1
Mediator of DNA damage checkpoint protein 1

1

1

High-throughput

0.479

High

1312374

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

1

High-throughput

0.479

High

980235

H4
Histone H4

1

0

High-throughput

0.458

High

1311921

SLF2
SMC5-SMC6 complex localization factor protein 2

1

0

High-throughput

0.458

High

1412504

TINF2
TERF1-interacting nuclear factor 2

1

0

Small-scale

0.458

High

1412508

XRN2
5'-3' exoribonuclease 2

1

0

Small-scale

0.458

High

107416

F8W7U8
Double-strand break repair protein

1

1

High-throughput

0.445

High

1217680

AXA81
Annexin A8-like protein 1

1

3

High-throughput

0.439

High

568976

ANXA8
Annexin A8

1

3

High-throughput

0.437

High

1118573

TBB2A
Tubulin beta-2A chain

1

3

High-throughput

0.437

High

1151635

TRIP6
Thyroid receptor-interacting protein 6

1

1

Small-scale

0.437

High

1372009

LPP
Lipoma-preferred partner

1

1

Small-scale

0.437

High

1412522

TFR2
Transferrin receptor protein 2

1

1

Small-scale

0.437

High

96012

E7EWX6
NAD-dependent protein deacetylase sirtuin-2

1

1

High-throughput

0.407

High

104675

F6U1T9
Protein phosphatase 3 regulatory subunit B, alpha

1

1

High-throughput

0.407

High

114473

H0Y9L7
TATA-box binding protein associated factor 1

1

1

High-throughput

0.407

High

1412511

PAAT
ATPase PAAT

2

0

High-throughput

0.328

High

132945

ST1C2
Sulfotransferase 1C2

1

0

High-throughput

0.299

High

221289

DCX
Neuronal migration protein doublecortin

1

0

High-throughput

0.299

High

262161

NOL3
Nucleolar protein 3

1

0

High-throughput

0.299

High

409060

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.299

High

479163

ENOG
Gamma-enolase

1

0

High-throughput

0.299

High

573227

KPYM
Pyruvate kinase PKM

1

0

High-throughput

0.299

High

660715

IF4B
Eukaryotic translation initiation factor 4B

1

0

High-throughput

0.299

High

834132

IPP2
Protein phosphatase inhibitor 2

1

0

High-throughput

0.299

High

896297

PEX5
Peroxisomal targeting signal 1 receptor

1

0

High-throughput

0.299

High

912602

GDIR1
Rho GDP-dissociation inhibitor 1

1

0

High-throughput

0.299

High

966817

1433G
14-3-3 protein gamma

1

0

High-throughput

0.299

High

1034519

TAGL
Transgelin

1

0

High-throughput

0.299

High

1052095

CALD1
Caldesmon

1

0

High-throughput

0.299

High

1160738

DREB
Drebrin

1

0

High-throughput

0.299

High

1192169

LEGL
Galectin-related protein

1

0

High-throughput

0.299

High

1275890

PAGE2
P antigen family member 2

1

0

High-throughput

0.299

High

1308402

ANKY2
Ankyrin repeat and MYND domain-containing protein 2

1

0

High-throughput

0.299

High

1328662

KCD17
BTB/POZ domain-containing protein KCTD17

1

0

High-throughput

0.299

High

1390932

SCRN2
Secernin-2

1

0

High-throughput

0.299

High

1398536

CCD43
Coiled-coil domain-containing protein 43

1

0

High-throughput

0.299

High

1411066

TXD17
Thioredoxin domain-containing protein 17

1

0

High-throughput

0.299

High

1412519

NCDN
Neurochondrin

1

0

High-throughput

0.299

High

1412524

CCDC9
Coiled-coil domain-containing protein 9

1

0

High-throughput

0.299

High

358790

LDHA
L-lactate dehydrogenase A chain

1

0

High-throughput

0.288

High

365774

KAD1
Adenylate kinase isoenzyme 1

1

0

High-throughput

0.288

High

366682

ADA
Adenosine deaminase

1

0

High-throughput

0.288

High

553271

KCRB
Creatine kinase B-type

1

0

High-throughput

0.288

High

653774

CRYGS
Gamma-crystallin S

1

0

High-throughput

0.288

High

884788

SYSC
Serine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.288

High

1032533

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

0

High-throughput

0.288

High

1059237

TISB
mRNA decay activator protein ZFP36L1

1

0

High-throughput

0.288

High

1131930

GNMT
Glycine N-methyltransferase

1

0

High-throughput

0.288

High

1244284

ZN790
Zinc finger protein 790

1

0

High-throughput

0.288

High

1289396

URP2
Fermitin family homolog 3

1

0

High-throughput

0.288

High

1293656

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.288

High

1308058

ABC3F
DNA dC->dU-editing enzyme APOBEC-3F

1

0

High-throughput

0.288

High

1315214

REM2
GTP-binding protein REM 2

1

0

High-throughput

0.288

High

1327006

AF1L2
Actin filament-associated protein 1-like 2

1

0

High-throughput

0.288

High

1337795

DP13B
DCC-interacting protein 13-beta

1

0

High-throughput

0.288

High

1412507

OR2H1
Olfactory receptor 2H1

1

0

High-throughput

0.288

High

1412515

DPP3
Dipeptidyl peptidase 3

1

0

High-throughput

0.288

High

1412520

BIN2
Bridging integrator 2

1

0

High-throughput

0.288

High

733060

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

0

High-throughput

0.282

High

1154724

VAMP3
Vesicle-associated membrane protein 3

1

0

High-throughput

0.279

Low

1291034

PACS2
Phosphofurin acidic cluster sorting protein 2

1

0

High-throughput

0.279

Low

1326765

CCD82
Coiled-coil domain-containing protein 82

1

0

High-throughput

0.279

Low

1368941

GOGA1
Golgin subfamily A member 1

1

0

High-throughput

0.279

Low

1386137

GCC1
GRIP and coiled-coil domain-containing protein 1

1

0

High-throughput

0.279

Low

1412509

EHD1
EH domain-containing protein 1

1

0

High-throughput

0.279

Low

1412518

DPM3
Dolichol-phosphate mannosyltransferase subunit 3

1

0

High-throughput

0.279

Low

1349828

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

0

High-throughput

0.269

Low

880954

MTR1B
Melatonin receptor type 1B

1

0

High-throughput

0.265

Low

1412514

PK1IP
p21-activated protein kinase-interacting protein 1

1

0

Small-scale

0.251

Low

1219470

SLX4I
Protein SLX4IP

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025