HitPredict

Interactor 1: STA5A (P42229)
Signal transducer and activator of transcription 5A
Gene: STAT5A

Interactor 2: STA5B (P51692)
Signal transducer and activator of transcription 5B
Gene: STAT5B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.895

The method score is based on:

Property Details
Experiments 28514442, 33961781, 10358045, 9398404
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH2, STAT_alpha~STAT_bind, STAT_alpha~STAT_int, STAT_bind~STAT_bind, STAT_int~STAT_int
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
and 14 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 794
Hs

1 787
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Last updated: 15 Jul 2024