Protein: PP1B
Serine/threonine-protein phosphatase beta isoform (EC 3.1.3.16) (Protein flap wing)

Gene: PP1B, flw
Organism: Drosophila melanogaster
Interactions: 131
UniProt ID: P48462

Gene Ontology (top 5):
GO:0000164 - protein phosphatase type 1 complex
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

559026

PP12
Serine/threonine-protein phosphatase alpha-2 isoform

4

13

High-throughput

0.861

High

823746

SQH
Myosin regulatory light chain sqh

2

6

Small-scale

0.806

High

68613

A8JNP7
Inhibitor-2, isoform B

3

20

Small-scale

0.756

High

873617

Q9VEK8
GH07711p

2

20

Small-scale

0.754

High

873599

Q95TZ7
GH19182p

2

12

High-throughput

0.754

High

873592

Q8SWT8
Protein phosphatase 1 regulatory subunit

1

20

Small-scale

0.713

High

121650

M9PFV2
Myosin phosphatase targeting subunit 75D, isoform B

4

20

Small-scale

0.696

High

873633

Q9VRC5
E3 ubiquitin-protein ligase PPP1R11

1

11

High-throughput

0.656

High

873638

GBS76
Glycogen-binding subunit 76A

1

20

High-throughput

0.656

High

873635

Q9VUX7
GH16214p

3

17

Small-scale

0.640

High

873580

Q7K9H6
Zinc finger FYVE domain-containing protein

2

17

Small-scale

0.627

High

873567

Q0KI67
Myosin heavy chain-like, isoform G

1

12

High-throughput

0.621

High

873628

Q9VNF9
Ethanol sensitive with low memory, isoform A

1

2

High-throughput

0.621

High

52062

A1Z6L9
Heat shock protein 75 kDa, mitochondrial

1

4

High-throughput

0.618

High

873601

Q9V3C7
Inhibitor-2

2

20

High-throughput

0.617

High

873581

Q7KU01
Phosphatase 1 nuclear targeting subunit, isoform D

2

16

Small-scale

0.595

High

57200

DCR2
Endoribonuclease Dcr-2

2

6

High-throughput

0.584

High

68421

A8DYU0
Toucan, isoform F

2

17

High-throughput

0.584

High

121923

M9PGZ8
Smrter, isoform G

2

15

High-throughput

0.584

High

362465

ABL
Tyrosine-protein kinase Abl

2

4

High-throughput

0.584

High

704336

SYEP
Bifunctional glutamate/proline--tRNA ligase

2

2

High-throughput

0.584

High

873571

CAZ
RNA-binding protein cabeza

2

11

High-throughput

0.584

High

873574

Q5U0V7
phosphoinositide 5-phosphatase

2

2

High-throughput

0.584

High

873585

TRA1
Transcription-associated protein 1

2

10

High-throughput

0.584

High

873586

Q8IP45
Cullin 3, isoform F

2

11

High-throughput

0.584

High

873587

Q8IPH8
Myosin 28B1, isoform B

2

17

High-throughput

0.584

High

873598

Q94883
DNA replication-related element factor, isoform A

2

1

High-throughput

0.584

High

873608

Q9VB52
LD05287p

2

6

High-throughput

0.584

High

873609

Y5521
Probable Rho GTPase-activating protein CG5521

2

7

High-throughput

0.584

High

873613

Q9VCE2
LD03179p

2

1

High-throughput

0.584

High

873616

Q9VE37
Mitogen-activated protein kinase kinase kinase 4

2

15

High-throughput

0.584

High

873619

Q9VFH5
Cadherin 88C

2

4

High-throughput

0.584

High

873627

Q9VNE0
PHD and RING finger domain-containing protein 1

2

14

High-throughput

0.584

High

873629

KP58
Serine/threonine-protein kinase PITSLRE

2

14

High-throughput

0.584

High

873637

SGF11
SAGA-associated factor 11 homolog

2

1

High-throughput

0.584

High

873639

MED12
Mediator of RNA polymerase II transcription subunit 12

2

9

High-throughput

0.584

High

873647

Q9W179
Sterile20-like kinase, isoform B

2

20

High-throughput

0.584

High

873652

Q9W2Z4
DNA replication ATP-dependent helicase/nuclease

2

3

High-throughput

0.584

High

873654

Q9W3W6
Small ovary, isoform A

2

3

High-throughput

0.584

High

873565

KTU
Protein kintoun

1

9

High-throughput

0.573

High

873573

Q4V424
IP09433p

1

20

High-throughput

0.555

High

873579

Q7K5M6
GH04176p

1

10

Small-scale

0.553

High

873607

Q9VAY2
Heat shock protein 83

1

2

High-throughput

0.553

High

873603

Q9V7W9
Nuclear inhibitor of protein phosphatase 1

2

9

Small-scale

0.543

High

873589

RS8
Small ribosomal subunit protein eS8

2

3

High-throughput

0.535

High

54417

A1Z8J5
Shavenoid, isoform A

2

1

High-throughput

0.533

High

118483

M9NEC2
chitinase

2

11

High-throughput

0.533

High

521079

XDH
Xanthine dehydrogenase

2

1

High-throughput

0.533

High

873560

TRPL
Transient-receptor-potential-like protein

2

2

High-throughput

0.533

High

873562

PROML
Prominin-like protein

2

1

High-throughput

0.533

High

873568

Q1LZ38
Dynein, axonemal, heavy chain 3, isoform E

2

1

High-throughput

0.533

High

873582

Q7KV70
Karst, isoform C

2

13

High-throughput

0.533

High

873602

Q9V483
Unc-13, isoform C

2

5

High-throughput

0.533

High

873606

Q9VAD3
Vacuolar protein sorting 13B, isoform A

2

1

High-throughput

0.533

High

873610

Q9VBD6
RT03118p

2

5

High-throughput

0.533

High

873612

Q9VC60
BUD13 homolog

2

7

High-throughput

0.533

High

873614

Q9VDG0
Dynein heavy chain at 93AB, isoform B

2

6

High-throughput

0.533

High

873618

CAD89
Cadherin-89D

2

4

High-throughput

0.533

High

873625

POE
Protein purity of essence

2

3

High-throughput

0.533

High

873626

Q9VMG8
Uncharacterized protein

2

1

High-throughput

0.533

High

873645

OSM1
Intraflagellar transport protein 172 homolog

2

3

High-throughput

0.533

High

873655

Q9W3X0
Uncharacterized protein, isoform A

2

6

High-throughput

0.533

High

633972

TRX
Histone-lysine N-methyltransferase trithorax

1

5

High-throughput

0.508

High

873578

MARS
Guanylate kinase-associated protein mars

1

5

High-throughput

0.508

High

873583

Q86B80
Uncharacterized protein, isoform A

1

3

High-throughput

0.508

High

873595

Q8T0D1
LD10183p

1

3

High-throughput

0.508

High

873648

Q9W1E4
GH11727p

1

3

High-throughput

0.508

High

118598

M9NF08
ZAP3, isoform D

1

7

High-throughput

0.481

High

843065

CBPD
Carboxypeptidase D

1

2

High-throughput

0.481

High

873596

Q8T0D9
LD08718p

1

1

High-throughput

0.481

High

873597

ENA
Protein enabled

1

10

High-throughput

0.481

High

873604

NUBPL
Iron-sulfur cluster transfer protein Nubpl

1

4

High-throughput

0.481

High

873621

Q9VIP4
LP17758p

1

14

High-throughput

0.481

High

873631

Q9VPY2
Phospholipase A2 activator protein, isoform A

1

13

High-throughput

0.481

High

873641

CP306
Cytochrome P450 306a1

1

1

High-throughput

0.481

High

873644

BAP60
Brahma-associated protein of 60 kDa

1

1

High-throughput

0.481

High

68148

A8DY69
phosphatidate phosphatase

1

5

High-throughput

0.479

High

119664

M9PB30
Dumpy, isoform Q

1

4

High-throughput

0.479

High

121043

M9PEP8
Muscle-specific protein 300 kDa, isoform M

1

8

High-throughput

0.479

High

432178

MYSA
Myosin heavy chain, muscle

1

9

High-throughput

0.479

High

688354

SOS
Protein son of sevenless

1

5

High-throughput

0.479

High

855974

MOEH
Moesin/ezrin/radixin homolog 1

1

10

Small-scale

0.479

High

873561

TIM
Protein timeless

1

3

Small-scale

0.479

High

873563

SMO
Protein smoothened

1

12

Small-scale

0.479

High

873570

MERH
Moesin/ezrin/radixin homolog 2

1

11

Small-scale

0.479

High

873600

MYSN
Myosin heavy chain, non-muscle

1

9

High-throughput

0.479

High

873624

TRM1
tRNA

1

1

High-throughput

0.479

High

873646

URI
Unconventional prefoldin RPB5 interactor-like protein

1

3

Small-scale

0.479

High

873650

Q9W2J2
Ankyrin-repeat, SH3-domain, and Proline-rich-region containing protein, isoform A

1

20

Small-scale

0.479

High

873591

Q8MRN4
GH12664p

1

3

High-throughput

0.464

High

873615

Q9VDX4
MIP05121p

1

3

High-throughput

0.464

High

873622

Q9VK43
LD10135p

1

3

High-throughput

0.464

High

873632

Q9VQS4
Spindly

1

3

High-throughput

0.464

High

873640

Q9VWB7
LD06925p

1

6

High-throughput

0.464

High

68292

A8DYE8
Stac-like, isoform M

1

0

High-throughput

0.458

High

873643

Q9VYE7
Kinase

1

0

High-throughput

0.458

High

447917

TPM1
Tropomyosin-1, isoforms 9A/A/B

1

9

High-throughput

0.457

High

873575

Q7JMZ1
Kinesin-like protein

1

14

High-throughput

0.457

High

873584

Q86R99
Protein phosphatase 1 regulatory subunit 12B

1

20

High-throughput

0.457

High

873588

Q8IQB4
Z band alternatively spliced PDZ-motif protein 66, isoform E

1

8

High-throughput

0.457

High

873593

Q8SY34
LD46604p

1

20

High-throughput

0.457

High

873651

Q9W2Y5
YLP motif-containing protein 1

1

11

High-throughput

0.457

High

54806

A1Z8Z8
Uncharacterized protein

1

1

High-throughput

0.439

High

58129

A1ZBF1
FI16628p1

1

3

High-throughput

0.439

High

234830

O46070
EG:25E8.4 protein

1

1

High-throughput

0.439

High

873569

Q1W9Q0
Echinus splice form 1

1

7

High-throughput

0.439

High

873576

Q7JZJ3
Cuticular protein 56F

1

1

High-throughput

0.439

High

873577

LCP2A
Cuticular protein 47Eg

1

1

High-throughput

0.439

High

873594

Q8SZP2
RE71854p

1

5

High-throughput

0.439

High

873620

Q9VIL2
LD19544p

1

1

High-throughput

0.439

High

873623

Q9VK57
PIH1 domain-containing protein 1

1

9

High-throughput

0.439

High

873634

Q9VUL2
GH20023p

1

1

High-throughput

0.439

High

873653

IDGF4
Chitinase-like protein Idgf4

1

3

High-throughput

0.439

High

873656

Q9W4I4
Helix loop helix protein 4C, isoform A

1

3

High-throughput

0.439

High

873657

R9PY70
Uncharacterized protein, isoform G

1

7

High-throughput

0.439

High

873658

X2JKX2
Corolla, isoform B

1

7

High-throughput

0.439

High

51973

A1Z6J6
Uncharacterized protein

1

1

High-throughput

0.437

High

716066

ITPR
Inositol 1,4,5-trisphosphate receptor

1

4

High-throughput

0.437

High

782847

TNNI
Troponin I

1

1

High-throughput

0.437

High

873564

Q0E8P6
Dynein heavy chain, cytoplasmic

1

6

High-throughput

0.437

High

873566

Q0KI05
Uncharacterized protein

1

6

High-throughput

0.437

High

873572

VATA2
V-type proton ATPase catalytic subunit A isoform 2

1

2

High-throughput

0.437

High

873611

Q9VBE2
RE40518p

1

5

High-throughput

0.437

High

873630

Q9VPK3
AT24407p

1

1

High-throughput

0.437

High

873636

Q9VVA4
Glutamate synthase [NADH]

1

3

High-throughput

0.437

High

873649

Q9W1R3
Golgin-245

1

17

High-throughput

0.437

High

305317

O77283
Echinus

1

7

High-throughput

0.417

High

482737

TPM2
Tropomyosin-2

1

8

High-throughput

0.417

High

873605

Q9V9N7
GH01875p

1

7

High-throughput

0.417

High

873642

Q9VX37
Corolla, isoform A

1

7

High-throughput

0.417

High

873590

Q8MME7
Uncharacterized protein, isoform L

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025