HitPredict

Interactor 1: GRIA1 (P42261)
Glutamate receptor 1 (GluR-1) (AMPA-selective glutamate receptor 1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1)
Gene: GRIA1

Interactor 2: E41L1 (Q9H4G0)
Band 4.1-like protein 1 (Erythrocyte membrane protein band 4.1-like 1) (Neuronal protein 4.1) (4.1N)
Gene: EPB41L1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	12574408, 11050113
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 906 Hs			1 881
+	Rn
		585158 GRIA1_RAT (1-906): 0: 942: 97.91		E41L1_RAT (1-881): 0: 705: 95.01
+	Hs
		816225 GRIA4_HUMAN (6-906): 0: 855: 66.52		E41L1_HUMAN (1-881): 0: 718: 100.00
+	Rn
		585225 GRIA4_RAT (6-906): 0: 856: 67.18		E41L1_RAT (1-881): 0: 705: 95.01
+	Hs
		204626 GRIA1_HUMAN (1-906): 0: 951: 100.00		E41L2_HUMAN (3-875): 0: 561: 42.93
+	Hs
		203180 GRID2_HUMAN (1-895): 0: 599: 24.82		PTN4_HUMAN (69-722): 5.38e-160: 493: 29.29
+	Mm
		1142979 GRID2_MOUSE (1-895): 0: 600: 24.71		PTN4_MOUSE (69-722): 2.94e-156: 483: 28.85
+	Hs
		816228 GRIA4_HUMAN (6-906): 0: 855: 66.52		E41L3_HUMAN (458-875): 1.5e-50: 195: 29.79
+	Hs
		505583 GRIA4_HUMAN (6-906): 0: 855: 66.52		EPB41_HUMAN (528-872): 1.64e-35: 147: 21.88
+	Ce
		656940 GLR1_CAEEL (2-876): 0: 585: 35.26		PTP1_CAEEL (73-794): 3.94e-120: 390: 24.26
+	Dm
		1353146 Q9TVI0_DROME (1-893): 0: 651: 29.88		EPB41_DROME (611-868): 1.57e-21: 103: 21.84
+	Dm
		1360339 Q9VMP4_DROME (1-859): 0: 597: 27.28		EPB41_DROME (611-868): 1.57e-21: 103: 21.84
+	Dm
		1360340 Q9VPV3_DROME (7-888): 0: 589: 25.27		EPB41_DROME (611-868): 1.57e-21: 103: 21.84