HitPredict

Interactor 1: GRIA1 (P42261)
Glutamate receptor 1 (GluR-1) (AMPA-selective glutamate receptor 1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1)
Gene: GRIA1

Interactor 2: PICK1 (Q9NRD5)
PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein)
Gene: PICK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	11891216
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0030666 - endocytic vesicle membrane GO:0060292 - long-term synaptic depression
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 906 Hs			1 415
+	Rn
		585217 GRIA4_RAT (6-906): 0: 856: 67.18		PICK1_RAT (1-415): 0: 597: 96.39
+	Hs
		816226 GRIA4_HUMAN (6-906): 0: 855: 66.52		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Rn
		585182 GRIA2_RAT (1-840): 0: 829: 71.95		PICK1_RAT (1-415): 0: 597: 96.39
+	Rn
		585195 GRIA3_RAT (1-849): 0: 829: 68.92		PICK1_RAT (1-415): 0: 597: 96.39
+	Hs
		786764 GRIA3_HUMAN (1-849): 0: 832: 68.92		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Hs
		786746 GRIA2_HUMAN (1-840): 0: 831: 72.07		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Mm
		620964 GRIA2_MOUSE (1-840): 0: 829: 71.95		PICK1_MOUSE (1-415): 0: 584: 94.47
+	Rn
		786686 GRIK2_RAT (8-889): 0: 798: 38.05		PICK1_RAT (1-415): 0: 597: 96.39
+	Hs
		1022367 GRIK2_HUMAN (8-889): 0: 799: 38.05		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Hs
		761212 GRIK1_HUMAN (6-892): 0: 788: 37.66		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Rn
		611607 GRIK1_RAT (6-863): 0: 775: 37.61		PICK1_RAT (1-415): 0: 597: 96.39