HitPredict

Interactor 1: MTREX (P42285)
Exosome RNA helicase MTR4 (EC 3.6.4.13) (ATP-dependent RNA helicase DOB1) (ATP-dependent RNA helicase SKIV2L2) (Superkiller viralicidic activity 2-like 2) (TRAMP-like complex helicase)
Gene: MTREX

Interactor 2: RBM11 (P57052)
Splicing regulator RBM11 (RNA-binding motif protein 11)
Gene: RBM11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1042 Hs			1 281
+	Hs
		787040 MTREX_HUMAN (1-1042): 0: 899: 100.00		RBM7_HUMAN (1-267): 7.89e-34: 125: 31.85
+	Hs
		787035 MTREX_HUMAN (1-1042): 0: 899: 100.00		PPIE_HUMAN (10-90): 1.92e-12: 67.8: 32.96
+	Sc
		376837 MTR4_YEAST (61-1042): 0: 723: 52.39		PABP_YEAST (6-99): 1.95e-18: 86.8: 23.16
+	Sp
		143097 YE02_SCHPO (22-1042): 0: 669: 46.04		PABP_SCHPO (2-94): 4.93e-20: 91.4: 23.66
+	Hs
		1272480 DHX36_HUMAN (6-926): 2.72e-106: 357: 12.46		DAZL_HUMAN (3-264): 6.63e-33: 123: 19.32
+	Hs
		1271707 DDX17_HUMAN (66-594): 5.59e-93: 314: 11.35		RBM7_HUMAN (1-267): 7.89e-34: 125: 31.85
+	Hs
		516589 ASCC3_HUMAN (14-634): 8.79e-97: 339: 17.59		PABP1_HUMAN (2-99): 9.14e-20: 90.7: 22.22
+	Hs
		571469 DDX5_HUMAN (18-569): 2.43e-96: 319: 12.00		ELAV1_HUMAN (2-133): 2.8e-20: 90.6: 17.24
+	Hs
		1073611 DDX17_HUMAN (66-594): 5.59e-93: 314: 11.35		SF3B4_HUMAN (9-111): 3.63e-21: 94: 26.67
+	Hs
		1077436 DDX17_HUMAN (66-594): 5.59e-93: 314: 11.35		ELAV1_HUMAN (2-133): 2.8e-20: 90.6: 17.24
+	Mm
		857351 Q8BTS0_MOUSE (18-569): 3.03e-96: 319: 11.83		TIA1_MOUSE (5-98): 4.45e-16: 79.1: 27.66
+	Sc
		697283 BRR2_YEAST (92-843): 2.28e-78: 284: 15.78		HSH49_YEAST (5-112): 1.04e-29: 113: 30.63
+	Mm
		857323 DDX17_MOUSE (66-594): 1.06e-93: 314: 11.35		TIA1_MOUSE (5-98): 4.45e-16: 79.1: 27.66
+	Hs
		571634 DDX5_HUMAN (18-569): 2.43e-96: 319: 12.00		PPIE_HUMAN (10-90): 1.92e-12: 67.8: 32.96
+	Hs
		1271695 DDX17_HUMAN (66-594): 5.59e-93: 314: 11.35		PPIE_HUMAN (10-90): 1.92e-12: 67.8: 32.96
+	Sc
		624051 DBP2_YEAST (1-565): 8.16e-93: 308: 11.53		PUB1_YEAST (6-94): 3.99e-14: 73.6: 29.21
+	Sc
		376698 BRR2_YEAST (92-843): 2.28e-78: 284: 15.78		PABP_YEAST (6-99): 1.95e-18: 86.8: 23.16
+	Sc
		693959 BRR2_YEAST (92-843): 2.28e-78: 284: 15.78		PUB1_YEAST (6-94): 3.99e-14: 73.6: 29.21
+	Sc
		694155 SLH1_YEAST (31-653): 6.6e-78: 282: 16.52		PUB1_YEAST (6-94): 3.99e-14: 73.6: 29.21
+	Sp
		678721 BRR2_SCHPO (92-842): 1.31e-64: 242: 14.90		PABP_SCHPO (2-94): 4.93e-20: 91.4: 23.66