HitPredict

Interactor 1: MTREX (P42285)
Exosome RNA helicase MTR4 (EC 3.6.4.13) (ATP-dependent RNA helicase DOB1) (ATP-dependent RNA helicase SKIV2L2) (Superkiller viralicidic activity 2-like 2) (TRAMP-like complex helicase)
Gene: MTREX

Interactor 2: NCBP1 (Q09161)
Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit)
Gene: NCBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	26496610, 32960270
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	DEAD~MIF4G, Helicase_C~MIF4G
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006401 - RNA catabolic process
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1042 Hs			1 790
+	Hs
		998104 DHX29_HUMAN (25-873): 2.11e-92: 324: 13.43		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		571416 DDX5_HUMAN (18-569): 2.43e-96: 319: 12.00		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		998141 DDX17_HUMAN (66-594): 5.59e-93: 314: 11.35		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		272111 U520_HUMAN (87-826): 1.97e-76: 278: 15.66		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Sp
		142999 YE02_SCHPO (22-1042): 0: 669: 46.04		NCBP1_SCHPO (3-664): 0: 652: 21.31
+	Sc
		697196 BRR2_YEAST (92-843): 2.28e-78: 284: 15.78		NCBP1_YEAST (3-693): 2.4e-99: 329: 17.53