Protein: PLCL2
Inactive phospholipase C-like protein 2 (PLC-L(2)) (PLC-L2) (Phospholipase C-L2) (Phospholipase C-epsilon-2) (PLC-epsilon-2)

Gene: PLCL2
Organism: Homo sapiens
Interactions: 22
UniProt ID: Q9UPR0

Gene Ontology (top 5):
GO:0002322 - B cell proliferation involved in immune response
GO:0002337 - B-1a B cell differentiation
GO:0004435 - phosphatidylinositol-4,5-bisphosphate phospholipase C activity
GO:0005737 - cytoplasm
GO:0007214 - gamma-aminobutyric acid signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

968039

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

5

2

High-throughput

0.722

High

786935

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

5

2

High-throughput

0.716

High

375019

RASH
GTPase HRas

1

19

High-throughput

0.665

High

376102

RASK
GTPase KRas

1

20

High-throughput

0.618

High

712902

CASP1
Caspase-1

2

0

High-throughput

0.602

High

892440

MTHFS
5-formyltetrahydrofolate cyclo-ligase

2

0

High-throughput

0.585

High

968488

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

2

High-throughput

0.536

High

442528

GELS
Gelsolin

1

4

High-throughput

0.515

High

1431896

PPIL3
Peptidyl-prolyl cis-trans isomerase-like 3

1

1

High-throughput

0.489

High

1114670

CUL3
Cullin-3

1

1

High-throughput

0.479

High

1462551

SHOC2
Leucine-rich repeat protein SHOC-2

1

2

High-throughput

0.479

High

650491

FGFR3
Fibroblast growth factor receptor 3

1

20

High-throughput

0.470

High

1461053

TNIK
TRAF2 and NCK-interacting protein kinase

1

3

High-throughput

0.457

High

106863

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

1382006

CK052
Uncharacterized protein C11orf52

1

2

High-throughput

0.437

High

1199760

KLH22
Kelch-like protein 22

1

0

High-throughput

0.426

High

1350831

DSCL1
Cell adhesion molecule DSCAML1

1

0

Small-scale

0.265

Low

1142025

EEA1
Early endosome antigen 1

1

0

High-throughput

0.249

Low

1277072

CC186
Coiled-coil domain-containing protein 186

1

0

High-throughput

0.249

Low

1312898

PDZD9
PDZ domain-containing protein 9

1

0

High-throughput

0.249

Low

1357839

S35F5
Solute carrier family 35 member F5

1

0

High-throughput

0.249

Low

1351616

MIPT3
TRAF3-interacting protein 1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025