Interactor 1: ACV1B (P36896)
Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)
Gene: ACVR1B
Interactor 2: AVR2B (Q13705)
Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)
Gene: ACVR2B
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.82 | 1.00 | 0.908 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 8622651, 8612709, 33961781, 12364468, unassigned3799 |
| Identification Methods | biochemical, affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | association, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Activin_recp~Activin_recp, Pkinase~Pkinase, Pkinase~TGF_beta_GS |
| Common GO terms | GO:0004674 - protein serine/threonine kinase activity GO:0005524 - ATP binding GO:0005886 - plasma membrane GO:0006355 - regulation of DNA-templated transcription GO:0007165 - signal transduction and 10 others more... |
| Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
