Interactor 1: MTOR (P42345)
Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1)
Gene: MTOR

Interactor 2: MTOR (P42345)
Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1)
Gene: MTOR

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 18030348, 16870609, 17360675, 19299511, 34171383, 9334222, 19225151, 24670654, 11438723
Identification Methods enzymatic study, affinity chromatography technology, in-gel kinase assay, anti tag coimmunoprecipitation, protein kinase assay, beta lactamase complementation
Interaction Type direct interaction, physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains DUF3385~FAT, DUF3385~PI3_PI4_kinase, FAT~FAT, FAT~FATC, FAT~PI3_PI4_kinase, FATC~PI3_PI4_kinase, FRB_dom~FRB_dom, FRB_dom~PI3_PI4_kinase, PI3_PI4_kinase~PI3_PI4_kinase
Common GO terms GO:0000139 - Golgi membrane
GO:0001002 - RNA polymerase III type 1 promoter sequence-specific DNA binding
GO:0001003 - RNA polymerase III type 2 promoter sequence-specific DNA binding
GO:0001006 - RNA polymerase III type 3 promoter sequence-specific DNA binding
GO:0001156 - TFIIIC-class transcription factor complex binding
and 110 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 2549
Hs

1 2549
+ Dm
+ Sc
+ At
+ Hs
+ Hs
+ Xl
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Sp
+ Sc
+ Hs
+ Sp

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Last updated: 15 Jul 2024